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脑死亡和循环停止后的器官捐献。

Organ Donation Following Neurologic and Circulatory Determination of Death.

机构信息

Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.

Division of Critical Care Medicine, Department of Pediatrics, Johns Hopkins All Children's Hospital, St. Petersburg, FL.

出版信息

Pediatr Crit Care Med. 2018 Aug;19(8S Suppl 2):S26-S32. doi: 10.1097/PCC.0000000000001518.

Abstract

OBJECTIVES

To describe important considerations during the process of caring for critically ill children who may be potential organ donors and supporting the family during the death of their child.

DESIGN

Literature review and expert commentary.

MEASUREMENT AND MAIN RESULTS

Medical literature focusing on pediatric donation, best pediatric donation practices, donor management, and factors influencing donation were reviewed. Additional pediatric data were obtained and reviewed from the U.S. Organ Procurement and Transplantation Network. Achieving successful organ donation requires the coordinated efforts of the critical care team, organ donation organization, and transplant team to effectively manage a potential donor and recover suitable organs for transplantation. Collaboration between these teams is essential to ensure that all potential organs are recovered in optimal condition, to reduce death and morbidity in children on transplantation waiting lists as well as fulfilling the family's wishes for their dying child to become a donor.

CONCLUSIONS

Organ donation is an important component of end-of-life care and can help the healing process for families and medical staff following the death of a child. The process of pediatric organ donation requires healthcare providers to actively work to preserve the option of donation before the death of the child and ensure donation occurs after consent/authorization has been obtained from the family. Medical management of the pediatric organ donor requires the expertise of a multidisciplinary medical team skilled in the unique needs of caring for children after neurologic determination of death and those who become donors following circulatory death after withdrawal of life-sustaining medical therapies.

摘要

目的

描述在照顾可能成为潜在器官捐献者的危重症儿童的过程中需要考虑的重要事项,并在儿童死亡时为其家庭提供支持。

设计

文献回顾和专家评论。

测量和主要结果

回顾了专注于儿科捐献、最佳儿科捐献实践、供者管理以及影响捐献的因素的医学文献。还从美国器官获取和移植网络获得并回顾了额外的儿科数据。实现成功的器官捐献需要重症监护团队、器官捐献组织和移植团队的协调努力,以有效地管理潜在供者并回收适合移植的器官。这些团队之间的协作对于确保所有潜在器官都以最佳状态回收、减少移植等待名单上儿童的死亡和发病率以及满足家庭希望其临终儿童成为供者的愿望至关重要。

结论

器官捐献是生命末期护理的重要组成部分,可以帮助家庭和医务人员在儿童死亡后治愈。儿科器官捐献的过程要求医疗保健提供者在儿童死亡前积极努力保留捐献的选择,并在获得家庭同意/授权后确保捐献发生。儿科器官捐献者的医疗管理需要多学科医疗团队的专业知识,这些团队熟练掌握在脑死亡后护理儿童的独特需求,以及在停止维持生命的医疗治疗后循环死亡成为供者的情况下的护理需求。

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