Institute of Biochemistry and Technical Biochemistry, Department of Food Chemistry , University of Stuttgart , Allmandring 5b , 70569 Stuttgart , Germany.
J Agric Food Chem. 2018 Aug 29;66(34):8935-8940. doi: 10.1021/acs.jafc.8b02265. Epub 2018 Aug 21.
Allergic reactions to food are among the major food safety concerns in industrialized countries, and it is estimated that approximately 5% of the population suffers from immunoglobulin-E-mediated food allergy. High-resolution mass spectrometry has become one of the most important techniques for the molecular characterization of allergens, including structural modification, degradation in the gastrointestinal environment, or identification of suitable marker peptides for the development of novel analytical approaches, in the past decade. This perspective aims to briefly summarize the current situation and discuss future developments.
食物过敏反应是工业化国家食品安全的主要关注点之一，据估计，约有 5%的人口患有免疫球蛋白 E 介导的食物过敏。在过去十年中，高分辨率质谱已成为过敏原分子特征描述的最重要技术之一，包括结构修饰、胃肠道环境中的降解或鉴定合适的标记肽，用于开发新的分析方法。本文旨在简要总结现状并讨论未来发展。
