Flepp M, Täuber M G, Lüthy R, Frauchiger B, Barandun J, Schütze M, Joller H, Frey-Wettstein M, Vetter W, Siegenthaler W
Schweiz Med Wochenschr. 1986 Apr 5;116(14):426-8.
Two patients developed signs of LAV/HTLV-III infection one and two years respectively after a blood transfusion. The leading symptom in one patient was generalized lymphadenopathy, while the other patient presented with Candida stomatitis. In both cases, blood transfusions administered in 1983 were found to be the only possible source of infection; one blood donor of each patient was anti-LAV/HTLV-III positive. Family members and sexual partners of the two were negative for antibodies against LAV/HTLV-III. Our findings document the first two cases of LAV/HTLV-III associated disease most probably related to blood transfusions in Switzerland.
两名患者分别在输血后一年和两年出现了淋巴结病相关病毒/人类嗜T淋巴细胞病毒III型(LAV/HTLV-III)感染迹象。其中一名患者的主要症状为全身性淋巴结病,而另一名患者表现为念珠菌性口腔炎。在这两例病例中,1983年所输的血液被认定为唯一可能的感染源;两名患者各自的一名献血者抗LAV/HTLV-III呈阳性。这两名患者的家庭成员和性伴侣的LAV/HTLV-III抗体均为阴性。我们的研究结果记录了瑞士首例最有可能与输血相关的两例LAV/HTLV-III相关疾病。