Siami K, Larras-Regard E
Acta Anat (Basel). 1986;125(3):165-73.
Intracytoplasmic crystalline bodies of various sizes are found in thyroid cells of 10-month-old mice and in younger animals under chronic lithium treatment. They are frequently surrounded by small microvesicles and dense bodies or enclosed in larger vesicles having a dense content. The crystalline skeleton is a network of protein fibers assembled in a characteristic axis with a periodicity of 8 nm. A deficiency of thyroid cell metabolism related to aging or lithium gluconate treatment would lead to an accumulation of substances of a crystalline pattern.
在10个月大的小鼠以及接受慢性锂治疗的幼龄动物的甲状腺细胞中发现了各种大小的胞质内晶体。它们常常被小微泡和致密体包围，或者被含有致密内容物的较大囊泡包裹。晶体骨架是由蛋白质纤维组成的网络，这些纤维以8纳米的周期沿特征轴组装。与衰老或葡萄糖酸锂治疗相关的甲状腺细胞代谢缺陷会导致晶体状物质的积累。
