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采用新型双分支支架型人工血管开放置入术进行全主动脉弓修复治疗急性A型主动脉夹层:21例连续患者的单中心经验

Total arch repair with open placement of a novel double-branched stent graft for acute Type A aortic dissection: a single-centre experience with 21 consecutive patients.

作者信息

Yu Bo, Liu ZhenHua, Xue Chao, Liu JinCheng, Yang Jian, Jin ZhenXiao, Yu ShiQiang, Duan WeiXun

机构信息

Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.

出版信息

Interact Cardiovasc Thorac Surg. 2019 Feb 1;28(2):262-269. doi: 10.1093/icvts/ivy243.

Abstract

OBJECTIVES

The aim of this study was to evaluate the safety and feasibility of total arch repair with open placement of a novel double-branched stent graft for acute Type A aortic dissection (TAAD).

METHODS

We retrospectively analysed the effect of the double-branched stent graft for total aortic arch placement with acute TAAD from December 2013 to February 2015. The effectiveness of the open placement of the double-branched stent graft was estimated by complete thrombus obliteration of the false lumen surrounding it on computed tomography angiography. Follow-up was performed at 6 months postoperatively and annually thereafter.

RESULTS

The double-branched stent graft was successfully placed into the true lumen of the descending aorta, aortic arch, left subclavian artery and left common carotid artery through the delivery system in 21 patients with acute TAAD. The mean cardiopulmonary bypass time was 210.2 ± 32.4 min, the mean aortic cross-clamp time was 94.9 ± 18.0 min, and the selective cerebral perfusion and deep hypothermia cardiopulmonary arrest time was 27.0 ± 10.4 min. The in-hospital mortality rate was 4.8%. The mean follow-up duration was 38.2 ± 12.5 months. No severe complications related to the surgery or residual dissection occurred during the follow-up. All survivors resumed normal activities.

CONCLUSIONS

The novel double-branched stent graft is proved to be safe and effective for total arch repair with acute TAAD in this study. It would be a new selective method for total arch repair in patients with acute TAAD.

CLINICAL REGISTRATION NUMBER

Research on pathogenic risk factors or characteristic features and clinical treatment of aortic dissection in Chinese Population (20120216-4).

摘要

目的

本研究旨在评估采用新型双分支支架型人工血管开放置入术进行全主动脉弓修复治疗急性A型主动脉夹层(TAAD)的安全性和可行性。

方法

我们回顾性分析了2013年12月至2015年2月期间采用双分支支架型人工血管进行全主动脉弓置入术治疗急性TAAD的效果。通过计算机断层扫描血管造影术观察其周围假腔完全血栓形成来评估双分支支架型人工血管开放置入的有效性。术后6个月进行随访,之后每年随访一次。

结果

21例急性TAAD患者通过输送系统成功将双分支支架型人工血管置入降主动脉、主动脉弓、左锁骨下动脉和左颈总动脉的真腔。平均体外循环时间为210.2±32.4分钟,平均主动脉阻断时间为94.9±18.0分钟,选择性脑灌注和深低温停循环时间为27.0±10.4分钟。院内死亡率为4.8%。平均随访时间为38.2±12.5个月。随访期间未发生与手术相关的严重并发症或残留夹层。所有幸存者均恢复了正常活动。

结论

本研究证明新型双分支支架型人工血管用于急性TAAD的全主动脉弓修复是安全有效的。它将成为急性TAAD患者全主动脉弓修复的一种新的选择方法。

临床注册号

中国人群主动脉夹层致病危险因素或特征及临床治疗研究(20120216 - 4)

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