From the Cardiology Clinical Academic Group, St. George's, University of London (A.M., H.D., G.F., S.G., M.T., M.P., S.S.), the Department of Sports Medicine, Bartholomew's and London Hospital (I.B.), and the Department of Cardiology, Imperial College NHS Trust (J.M., A.V.), London, the Football Association, Burton Upon Trent (A.M., C.C.), the Department of Cardiology, Queen Elizabeth Hospital, Birmingham (P.C.), the Department of Cardiology, Freeman Hospital, Newcastle Upon Tyne (A.K.), the Faculty of Science, Liverpool John Moores University (D.O., J.S.), and the Department of Cardiology, Liverpool Heart and Chest Hospital (D. Ramsdale), Liverpool, the Department of Cardiology, Good Hope Hospital, Sutton Coldfield (K.P.), Bristol Heart Institute, Bristol (G.P., G.S.), University Hospital Southampton, Southampton (D. Rakhit), the Department of Cardiology, Papworth Hospital, Papworth (L.S.), Nottingham City Hospital, Nottingham (J.W.), and the University Hospital of Wales, Cardiff (Z.Y.) - all in the United Kingdom.
N Engl J Med. 2018 Aug 9;379(6):524-534. doi: 10.1056/NEJMoa1714719.
Reports on the incidence and causes of sudden cardiac death among young athletes have relied largely on estimated rates of participation and varied methods of reporting. We sought to investigate the incidence and causes of sudden cardiac death among adolescent soccer players in the United Kingdom.
From 1996 through 2016, we screened 11,168 adolescent athletes with a mean (±SD) age of 16.4±1.2 years (95% of whom were male) in the English Football Association (FA) cardiac screening program, which consisted of a health questionnaire, physical examination, electrocardiography, and echocardiography. The FA registry was interrogated to identify sudden cardiac deaths, which were confirmed with autopsy reports.
During screening, 42 athletes (0.38%) were found to have cardiac disorders that are associated with sudden cardiac death. A further 225 athletes (2%) with congenital or valvular abnormalities were identified. After screening, there were 23 deaths from any cause, of which 8 (35%) were sudden deaths attributed to cardiac disease. Cardiomyopathy accounted for 7 of 8 sudden cardiac deaths (88%). Six athletes (75%) with sudden cardiac death had had normal cardiac screening results. The mean time between screening and sudden cardiac death was 6.8 years. On the basis of a total of 118,351 person-years, the incidence of sudden cardiac death among previously screened adolescent soccer players was 1 per 14,794 person-years (6.8 per 100,000 athletes).
Diseases that are associated with sudden cardiac death were identified in 0.38% of adolescent soccer players in a cohort that underwent cardiovascular screening. The incidence of sudden cardiac death was 1 per 14,794 person-years, or 6.8 per 100,000 athletes; most of these deaths were due to cardiomyopathies that had not been detected on screening. (Funded by the English Football Association and others.).
有关青少年运动员心源性猝死发生率和病因的报告在很大程度上依赖于参与率的估计和报告方法的差异。我们旨在调查英国青少年足球运动员心源性猝死的发生率和病因。
1996 年至 2016 年，我们在英格兰足球协会（FA）心脏筛查计划中对 11168 名平均（±标准差）年龄为 16.4±1.2 岁的青少年运动员（其中 95%为男性）进行了筛查，该计划包括健康问卷、体格检查、心电图和超声心动图。FA 注册处被询问以确定心源性猝死病例，这些病例均通过尸检报告得到确认。
在筛查过程中，发现 42 名运动员（0.38%）存在与心源性猝死相关的心脏疾病。另有 225 名（2%）运动员存在先天性或瓣膜异常。筛查后，共有 23 人死于任何原因，其中 8 人（35%）为心源性疾病导致的猝死。心肌病占 8 例心源性猝死中的 7 例（88%）。6 例（75%）心源性猝死运动员的心脏筛查结果正常。心源性猝死与筛查之间的平均时间为 6.8 年。基于总共 118351 人年，先前接受过筛查的青少年足球运动员中心源性猝死的发生率为每 14794 人年 1 例（6.8/10 万人运动员）。
在接受心血管筛查的队列中，0.38%的青少年足球运动员发现与心源性猝死相关的疾病。心源性猝死的发生率为每 14794 人年 1 例（6.8/10 万人运动员）；大多数死亡归因于筛查未能检测到的心肌病。（由英格兰足球协会和其他机构资助）。
