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确定导致孕妇阿片类药物使用障碍的阿片类药物滥用的开始。

Determining the Initiation of Opiate Misuse Resulting in Opioid Use Disorder in Pregnant Women.

机构信息

a Department of OB/GYN , Indiana University School of Medicine , Indianapolis , IN, USA.

b Department of Psychiatry , Midtown Community Mental Health Clinic, Eskenazi Health, Indianapolis, IN, USA.

出版信息

J Psychoactive Drugs. 2018 Sep-Oct;50(4):331-338. doi: 10.1080/02791072.2018.1497235. Epub 2018 Aug 8.

Abstract

The aim of this study was to explore the "opiate misuse footprint" made by obstetrics and gynecology physicians in prescribing opioid medications for postpartum pain control that led to opioid misuse and opioid use disorder. Data were collected using intake information and anonymous surveys administered to pregnant women at local methadone clinics in Indianapolis, Indiana, in 2016-2017. Results from this study revealed that 40% of the 33 participants stated that the first drug they became addicted to was prescription opioids; 71% stated that the first opiate they became addicted to was a prescription pain medication. Prescription opioids were mainly obtained from emergency medicine physicians and friends. Reported use of opioids within the past four months was high, with the most commonly used drugs being methadone (57.6%) and heroin (42.4%). A majority of participants also endorsed a history of sexual and physical abuse, recent incarceration, and mental health disorders. As a large number of pregnant women with opioid use disorder reported their initial drug of misuse as prescription pain medications, it is important to avoid overprescribing opioids in reproductive-age women.

摘要

本研究旨在探讨妇产科医生在开具阿片类药物治疗产后疼痛控制方面留下的“阿片类药物滥用足迹”,这些药物导致了阿片类药物滥用和阿片类药物使用障碍。数据采集自印第安纳波利斯当地美沙酮诊所 2016-2017 年对孕妇进行的入组信息和匿名调查。本研究结果显示,33 名参与者中有 40%表示,他们上瘾的第一种药物是处方阿片类药物;71%表示,他们上瘾的第一种阿片类药物是处方止痛药。处方阿片类药物主要从急诊医生和朋友那里获得。过去四个月内报告的阿片类药物使用量较高,最常使用的药物是美沙酮(57.6%)和海洛因(42.4%)。大多数参与者还承认有性虐待和身体虐待、最近监禁和精神健康障碍的病史。由于大量患有阿片类药物使用障碍的孕妇报告称,他们最初滥用的药物是处方止痛药,因此,避免在生育年龄的女性中过度开具阿片类药物非常重要。

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