Hiremath Shivanand B, Desai Mahesh
Department of Psychiatry, Karnataka Institute of Medical Sciences, Hubballi, Karnataka, India.
Ind Psychiatry J. 2017 Jul-Dec;26(2):188-193. doi: 10.4103/ipj.ipj_3_16.
Depression is the most prevalent psychiatric condition seen in human immunodeficiency virus (HIV)-positive individuals. Various biological, sociocultural, and economic factors make women more vulnerable to HIV and acquired immune deficiency syndrome (AIDS). Depression affects medication adherence and immunity against HIV thus contribute significantly to disease progression.
The aim is to assess the prevalence, sociodemographic, and clinical correlates of depression among women living with HIV/AIDS.
Antiretroviral therapy (ART) centre attached to government medical college hospital in North Karnataka and cross-sectional design.
This study was conducted among of 145 women living with HIV/AIDS, depression was assessed using Beck Depression Inventory, and social support was assessed using Lubben Social Network Scale and quality of life (QoL) using the World Health Organization QoL BREF scale.
Data were analyzed using Statistical Package for the Social Sciences version 20.0. Chi-square test with value less than 0.05 was taken as statistically significant.
Among 145 HIV-positive women, 50 (34.5%) were depressed. Depression was statistically significant in women from rural background. Significant association between depression and risk of social isolation was observed. Scores of all domains of QoL, that is, physical, psychological, social, and environmental were reducing with increase in the severity of depression indicating that QoL was decreasing with increase in severity of depression. Among the four domains, social domain was the most affected.
Depression among women living with HIV/AIDS which is underdiagnosed and undertreated. Depression negatively impacts adherence and immunity leading rapid progression of the infection. Therefore, early diagnosis and treatment of depression are essential.
抑郁症是人类免疫缺陷病毒(HIV)阳性个体中最常见的精神疾病。各种生物学、社会文化和经济因素使女性更容易感染HIV和获得性免疫缺陷综合征(AIDS)。抑郁症会影响药物依从性和对HIV的免疫力,从而对疾病进展有显著影响。
旨在评估感染HIV/AIDS的女性中抑郁症的患病率、社会人口学特征及临床相关因素。
北卡纳塔克邦政府医学院附属医院的抗逆转录病毒治疗(ART)中心,采用横断面设计。
本研究对145名感染HIV/AIDS的女性进行,使用贝克抑郁量表评估抑郁症,使用鲁本社会网络量表评估社会支持,并使用世界卫生组织生活质量简表评估生活质量(QoL)。
使用社会科学统计软件包20.0对数据进行分析。P值小于0.05的卡方检验被视为具有统计学意义。
在145名HIV阳性女性中,50名(34.5%)患有抑郁症。农村背景的女性中抑郁症具有统计学意义。观察到抑郁症与社会隔离风险之间存在显著关联。随着抑郁症严重程度的增加,生活质量的所有领域,即身体、心理、社会和环境领域的得分均降低,表明生活质量随着抑郁症严重程度的增加而下降。在这四个领域中,社会领域受影响最大。
感染HIV/AIDS的女性中的抑郁症未得到充分诊断和治疗。抑郁症对依从性和免疫力产生负面影响,导致感染迅速进展。因此,抑郁症的早期诊断和治疗至关重要。