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老年人双眼复视的病因、背景及特征

Causes, background, and characteristics of binocular diplopia in the elderly.

作者信息

Kawai Manami, Goseki Toshiaki, Ishikawa Hitoshi, Hoshina Miki, Shoji Nobuyuki

机构信息

Graduate School of Medical Sciences, Kitasato University, Sagamihara, Kanagawa, Japan.

Department of Ophthalmology, Kitasato University, 1-15-1, Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan.

出版信息

Jpn J Ophthalmol. 2018 Nov;62(6):659-666. doi: 10.1007/s10384-018-0617-2. Epub 2018 Aug 12.

Abstract

PURPOSE

We evaluated the background and characteristics of elderly patients with binocular diplopia including diseases caused by abnormalities in orbital pulleys.

STUDY DESIGN

Retrospective.

METHODS

The participants were 236 patients aged 60 years or older who visited Kitasato University Hospital complaining of binocular diplopia. We classified strabismus by types and investigated the causes for each group. We diagnosed orbital pulley disorders using magnetic resonance imaging (MRI). Patients with orbital pulley disorders exhibited esotropia and/or vertical strabismus and did not present with cranial nerve palsy, systemic illness, or ocular injury.

RESULTS

Classification of strabismus types was: exotropia (24.2%); esotropia (25.0%); vertical strabismus (30.1%), combined strabismus (20.8%). There were 50.9% cases of strabismus associated with vertical deviation. The causes of disease in each group were as follows: in the exotropia group, 50.9% convergence insufficiency exotropia, 21.1% basic exotropia; in the esotropia group: 35.6% orbital pulley disorder 33.9% sixth cranial nerve palsy; in the vertical strabismus group: 32.4% forth cranial nerve palsy, 31.0% orbital pulley disorder; in the combined strabismus group: 28.6% orbital pulley disorder, 28.6% forth cranial nerve palsy.

CONCLUSIONS

About half of the elderly patients with binocular diplopia exhibited vertical deviation. In addition, binocular diplopia was often caused by orbital pulley disorders. It is the first epidemiological study focusing on orbital pulley disorders diagnosed on the basis of MRI.

摘要

目的

我们评估了双眼复视老年患者的背景和特征,包括由眶滑车异常引起的疾病。

研究设计

回顾性研究。

方法

研究对象为236例60岁及以上因双眼复视而就诊于北里大学医院的患者。我们按类型对斜视进行分类,并调查每组的病因。我们使用磁共振成像(MRI)诊断眶滑车疾病。眶滑车疾病患者表现为内斜视和/或垂直斜视,且无颅神经麻痹、全身性疾病或眼部损伤。

结果

斜视类型分类如下:外斜视(24.2%);内斜视(25.0%);垂直斜视(30.1%),混合性斜视(20.8%)。有50.9%的斜视病例伴有垂直偏斜。每组疾病的病因如下:在外斜视组中,50.9%为集合不足性外斜视,21.1%为基本外斜视;在内斜视组中:35.6%为眶滑车疾病,33.9%为第六颅神经麻痹;在垂直斜视组中:32.4%为第四颅神经麻痹,31.0%为眶滑车疾病;在混合性斜视组中:28.6%为眶滑车疾病,28.6%为第四颅神经麻痹。

结论

约一半双眼复视的老年患者表现出垂直偏斜。此外,双眼复视常由眶滑车疾病引起。这是第一项聚焦于基于MRI诊断的眶滑车疾病的流行病学研究。

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