合成的胞壁酰二肽衍生物对病毒感染和机会性感染影响的实验与临床研究
Experimental and clinical studies on the effects of synthetic muramyldipeptide derivatives on viral and opportunistic infections.
作者信息
Yamamura Y, Ishihara C, Hamada N, Yamamoto K, Azuma I
出版信息
Methods Find Exp Clin Pharmacol. 1986 Jan;8(1):11-4.
PMID:3010013
Abstract
The efficacy of strearoyl-MDP derivatives, L18-MDP and MDP-Lys-18 against bacterial and viral infections in mice was examined. Both L18-MDP and MDP-Lys-L18 stimulated nonspecifically host-resistance against opportunistic infection with C. kutscheri in hydrocrotisone-treated mice against Sendai virus infection in mice.
摘要
研究了硬脂酰-MDP衍生物L18-MDP和MDP-Lys-18对小鼠细菌和病毒感染的疗效。L18-MDP和MDP-Lys-L18均非特异性地刺激宿主抵抗氢化可的松处理的小鼠中由库氏肺孢子虫引起的机会性感染，以及抵抗小鼠中的仙台病毒感染。
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