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麻醉医生对患有阻塞性睡眠呼吸暂停的大手术患者术后镇痛的偏好。

Anesthesiologist preference for postoperative analgesia in major surgery patients with obstructive sleep apnea.

作者信息

Bamgbade Olumuyiwa A

机构信息

Department of Anaesthesia, University of British Columbia, Vancouver, Canada.

出版信息

Saudi J Anaesth. 2018 Jul-Sep;12(3):475-477. doi: 10.4103/sja.SJA_25_18.

Abstract

Obstructive sleep apnea (OSA) is prevalent and presents perioperative challenges. There are guidelines regarding perioperative care of OSA, but analgesia management of OSA patients is inconsistent or inadequate. This is a study of the United Kingdom anesthesiologists' postoperative analgesia preferences for OSA patients. Overall, the 1 choice of main analgesia was continuous epidural local anesthetic (LA) without opioid, at 30% rate; = 0.001. The 2 choice was continuous epidural LA plus fentanyl, at 21% rate; = 0.001. The 3 choice was intrathecal diamorphine, at 19% rate; = 0.001. The 4 choice was nerve block catheter LA infusion, at 13% rate; = 0.001. The 5 choice was wound infiltration with LA ± epinephrine, at 8% rate; = 0.001. The 6 choice was systemic opioid, at 7% rate; = 0.007. The 7 choice was systemic nonsteroidal anti-inflammatory drugs, at 2% rate; = 0.001. The hospital setting or anesthesiologists' experience did not significantly impact analgesia choice: =0.411. This study shows that current practice by anesthesiologists has a preference for regional or opioid-sparing analgesia for OSA patients. This safe approach conforms to guidelines and should be encouraged.

摘要

阻塞性睡眠呼吸暂停(OSA)很常见,并且在围手术期会带来挑战。关于OSA围手术期护理有相关指南,但OSA患者的镇痛管理并不一致或不充分。这是一项关于英国麻醉医生对OSA患者术后镇痛偏好的研究。总体而言,主要镇痛方法的首选是不使用阿片类药物的持续硬膜外局部麻醉(LA),占比30%;P = 0.001。第二选择是持续硬膜外LA加芬太尼,占比21%;P = 0.001。第三选择是鞘内注射二醋吗啡,占比19%;P = 0.001。第四选择是神经阻滞导管LA输注,占比13%;P = 0.001。第五选择是用LA±肾上腺素进行伤口浸润,占比8%;P = 0.001。第六选择是全身性阿片类药物,占比7%;P = 0.007。第七选择是全身性非甾体抗炎药,占比2%;P = 0.001。医院环境或麻醉医生的经验对镇痛选择没有显著影响:P = 0.411。这项研究表明,麻醉医生目前的做法倾向于对OSA患者采用区域镇痛或阿片类药物节省镇痛。这种安全的方法符合指南,应该得到鼓励。

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本文引用的文献

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Survey of perioperative care of adults with obstructive sleep apnoea.
Eur J Anaesthesiol. 2009 Aug;26(8):706-8. doi: 10.1097/EJA.0b013e3283297555.
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Dexmedetomidine anaesthesia for patients with obstructive sleep apnoea undergoing bariatric surgery.
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