Loftus John P, Wakshlag Joseph J
Cornell University College of Veterinary Medicine, Veterinary Medical Center, Ithaca, NY, USA,
Vet Med (Auckl). 2014 Dec 30;6:49-60. doi: 10.2147/VMRR.S40868. eCollection 2015.
Canine and feline obesity rates have reached pandemic proportions and are similar to those in humans, with approximately 30%-40% of dogs and cats being overweight to obese. Obesity has been associated with other health problems, including osteoarthritis, renal disease, skin disease, insulin resistance, and neoplasia in dogs, while in cats obesity is associated with dermatological issues, diabetes mellitus, neoplasia, and urolithiasis. The health issues appear to be slightly different across the two species, which may be due to some inherent differences in the hormonal milieu involved in obesity that differs between the dog and the cat. In this review, we discuss the complicated nature of the pathogenesis of obesity, the hormonal stimulus for orexigenic and anorexigenic behavior, adipose tissue as an endocrine organ, and most importantly, clinical management of the number one disease in canine and feline medicine.
犬类和猫类的肥胖率已达到流行程度，与人类相似，约30%-40%的犬猫超重至肥胖。肥胖与其他健康问题有关，包括犬类的骨关节炎、肾病、皮肤病、胰岛素抵抗和肿瘤形成，而在猫中，肥胖与皮肤病、糖尿病、肿瘤形成和尿石症有关。这两个物种的健康问题似乎略有不同，这可能是由于犬猫在肥胖相关的激素环境中存在一些固有差异。在这篇综述中，我们讨论了肥胖发病机制的复杂性、促食欲和抑食欲行为的激素刺激、脂肪组织作为内分泌器官，以及最重要的是，犬猫医学中头号疾病的临床管理。
