University of Oviedo, Asturias, Spain, Hospital of Cabuenes, Asturias, Spain.
Curr Alzheimer Res. 2018;15(12):1142-1150. doi: 10.2174/1567205015666180813145402.
The expressive difficulties in patients with Alzheimer's dementia have been extensively studied, mainly in oral language. However, the deterioration of their writing processes has received much less attention.
The present study aims to examine the decline of the performance of patients with Alzheimer's disease in both oral and written picture-naming tasks.
Sixty-four participants (half with Alzheimer's disease and half healthy elderly) were compared in the oral and written versions of a picture-naming task. Follow-up lasted two and a half years and patients were evaluated every six months.
Cross-sectional data indicate that the controls performed better than the patients, and both groups showed a different pattern of errors. In terms of longitudinal data, the results show a similar pattern of deterioration in both tasks. In terms of errors, lexical-semantics were the most numerous at the beginning and their number remained constant throughout all evaluations. In the case of non-responses, there was a significant increase in the last session, both in oral and written naming.
These results replicate those found in previous studies and highlight the utility of the naming task to detect minimal changes in the evolution of patients with Alzheimer's disease.
阿尔茨海默病患者的表达困难已得到广泛研究，主要集中在口语上。然而，他们写作过程的恶化却受到较少关注。
本研究旨在检查阿尔茨海默病患者在口头和书面图片命名任务中的表现下降。
在口头和书面图片命名任务的两种版本中，比较了 64 名参与者（一半为阿尔茨海默病患者，一半为健康老年人）。随访持续了两年半，每六个月对患者进行一次评估。
横断面数据表明，对照组的表现优于患者组，两组均表现出不同的错误模式。就纵向数据而言，结果表明两个任务的恶化模式相似。在错误方面，词汇语义在开始时最多，并且在所有评估中数量保持不变。在无反应的情况下，无论是口头还是书面命名，最后一次评估的无反应数量都显著增加。
这些结果复制了之前研究中的发现，突出了命名任务在检测阿尔茨海默病患者病情演变中的微小变化方面的效用。
