Ikeoka Toshiyuki, Sako Ayaka, Kuriya Genpei, Yamashita Hiroshi, Yasuhi Ichiro, Horie Ichiro, Ando Takao, Abiru Norio, Kawakami Atsushi
Department of Endocrinology and Metabolism, National Hospital Organization Nagasaki Medical Center, Japan.
Department of Obstetrics and Gynecology, National Hospital Organization Nagasaki Medical Center, Japan.
Intern Med. 2018 Dec 1;57(23):3413-3418. doi: 10.2169/internalmedicine.1188-18. Epub 2018 Aug 10.
A 27-year-old woman with a history of gestational diabetes mellitus (GDM) developed type 1 diabetes mellitus (T1D) in the early postpartum period. Women with a history of GDM are at an increased risk of developing T1D, which is rarer than type 2 diabetes mellitus. A postpartum follow-up 75-g oral glucose tolerance test and the measurement of glutamic acid decarboxylase autoantibodies aided in the early detection of T1D in this patient. Careful attention should be paid to women with a history of GDM who exhibit clinical features suggestive of future development of T1D.
一名有妊娠期糖尿病（GDM）病史的27岁女性在产后早期发展为1型糖尿病（T1D）。有GDM病史的女性患T1D的风险增加，T1D比2型糖尿病更罕见。产后75克口服葡萄糖耐量试验及谷氨酸脱羧酶自身抗体检测有助于该患者T1D的早期诊断。对于有GDM病史且表现出提示未来可能发展为T1D临床特征的女性应予以密切关注。
