Department of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Diabetes Research Centre, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Int J Gynaecol Obstet. 2023 Jan;160 Suppl 1(Suppl 1):56-67. doi: 10.1002/ijgo.14537.
Gestational diabetes (GDM) impacts approximately 17 million pregnancies worldwide. Women with a history of GDM have an 8-10-fold higher risk of developing type 2 diabetes and a 2-fold higher risk of developing cardiovascular disease (CVD) compared with women without prior GDM. Although it is possible to prevent and/or delay progression of GDM to type 2 diabetes, this is not widely undertaken. Considering the increasing global rates of type 2 diabetes and CVD in women, it is essential to utilize pregnancy as an opportunity to identify women at risk and initiate preventive intervention. This article reviews existing clinical guidelines for postpartum identification and management of women with previous GDM and identifies key recommendations for the prevention and/or delayed progression to type 2 diabetes for global clinical practice.
妊娠期糖尿病(GDM)影响全球约 1700 万例妊娠。与无既往 GDM 的女性相比,有 GDM 病史的女性发生 2 型糖尿病的风险增加 8-10 倍,发生心血管疾病(CVD)的风险增加 2 倍。尽管可以预防和/或延缓 GDM 向 2 型糖尿病的进展,但这并未得到广泛实施。鉴于全球女性 2 型糖尿病和 CVD 的发病率不断上升,利用妊娠机会识别高危妇女并启动预防干预至关重要。本文回顾了现有关于产后识别和管理既往 GDM 妇女的临床指南,并为全球临床实践确定了预防和/或延缓 2 型糖尿病进展的关键建议。