分支 PCR 构建 TP53 基因纳米载体用于潜在的癌症治疗。
Branch-PCR constructed TP53 gene nanovector for potential cancer therapy.
机构信息
State Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center (Tianjin), Collaborative Innovation Center of Chemical Science and Engineering, (Tianjin), College of Chemistry, Nankai University, Tianjin, 300071, China.
出版信息
Chem Commun (Camb). 2018 Aug 23;54(69):9687-9690. doi: 10.1039/c8cc05066j.
PMID:30102306
Abstract
A novel and efficient branch PCR strategy has been used to construct a TP53 gene nanovector based on a pair of trimers as primers, which showed unique advantages compared to other existing systems for gene delivery and effective potential cancer therapy.
摘要
一种新颖有效的分支 PCR 策略已被用于构建基于三聚体作为引物的 TP53 基因纳米载体，与其他现有的基因传递系统相比，该策略具有独特的优势，并且具有有效的癌症治疗潜力。
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