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多发性颅神经鞘瘤和脑膜瘤作为儿童2型神经纤维瘤病的标志性体征。

Multiple cranial nerve schwannomas and meningiomas as a hallmark sign of neurofibromatosis type 2 in a child.

作者信息

Halefoğlu Ahmet Mesrur

机构信息

Department of Radiology, Sisli Hamidiye Etfal Training and Research Hospital, Sisli, Istanbul, Turkey.

出版信息

Turk J Pediatr. 2018;60(1):107-110. doi: 10.24953/turkjped.2018.01.018.

Abstract

Halefoğlu AM. Multiple cranial nerve schwannomas and meningiomas as a hallmark sign of neurofibromatosis type 2 in a child. Turk J Pediatr 2018; 60: 107-110. Neurofibromatosis type 2 is a rarely encountered autosomal dominant disorder manifesting with typical radiological findings. These patients have a predilection for development of benign tumors in the central nervous system. Although the presenting symptom is most commonly hearing loss due to acoustic schwannomas, symptoms emanating from other cranial tumors are not uncommon. Herein, we described a 16-year-old male patient presented with multiple meningiomas and cranial nerve schwannomas revealed by magnetic resonance imaging. He fulfilled the diagnostic criteria of neurofibromatosis type 2 and underwent treatment. We emphasized the role of radiology in the early diagnosis of this inherited disorder in order to provide a better prognosis.

摘要

哈莱福卢 AM。儿童多发性颅神经鞘瘤和脑膜瘤作为2型神经纤维瘤病的标志性体征。《土耳其儿科学杂志》2018年;60: 107 - 110。2型神经纤维瘤病是一种罕见的常染色体显性疾病,具有典型的影像学表现。这些患者易在中枢神经系统发生良性肿瘤。虽然最常见的症状是由于听神经鞘瘤导致的听力丧失,但其他颅部肿瘤引起的症状也并不少见。在此,我们描述了一名16岁男性患者,磁共振成像显示其患有多发性脑膜瘤和颅神经鞘瘤。他符合2型神经纤维瘤病的诊断标准并接受了治疗。我们强调了放射学在这种遗传性疾病早期诊断中的作用,以便获得更好的预后。

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