Massachusetts General Hospital, Department of Psychiatry, USA; Harvard Medical School, Department of Psychiatry, USA.
Harvard University, Department of Psychology, USA.
J Psychiatr Res. 2018 Sep;104:198-201. doi: 10.1016/j.jpsychires.2018.08.006. Epub 2018 Aug 3.
Patients suffering from borderline personality disorder (BPD) are at elevated risk for suicidal thoughts and behaviors (STBs), but this well-described and clinically important association is not well-understood. Prior research suggests that STBs often function as an attempt to escape aversive affect, and that people with BPD experience stronger emotion reactivity and greater discomfort with emotion than those without BPD. Here, we tested whether negative affective states are more likely to predict suicidal thoughts among those with BPD than those without this disorder. Data on affective states and suicidal thoughts were collected several times per day from 35 psychiatric inpatients using their smartphones to capture real-time associations between negative affect and suicidal thoughts. Results revealed that the association between negative affective states (e.g., abandonment, desperation, guilt, hopelessness, loneliness, rage, self-hatred, and upset), and severity of suicidal thinking was stronger among those with BPD than among those without BPD. This finding has implications for risk assessment and intervention in the clinical setting: for a given degree of reported negative affect, patients with BPD experience more suicidal ideation than those without. Further research needs to be done to elucidate the mechanism of this effect.
患有边缘型人格障碍 (BPD) 的患者自杀意念和行为 (STB) 的风险较高,但这种描述明确且在临床上很重要的关联尚未得到很好的理解。先前的研究表明,STB 通常是一种逃避不愉快情绪的尝试,而 BPD 患者比没有 BPD 的患者体验到更强的情绪反应和更大的情绪不适。在这里,我们测试了在 BPD 患者中,负面情绪状态是否比没有这种障碍的患者更有可能预测自杀意念。使用智能手机每天多次从 35 名精神病住院患者那里收集情感状态和自杀意念数据,以捕捉负面情绪和自杀意念之间的实时关联。结果表明,在 BPD 患者中,负面情绪状态(例如被抛弃、绝望、内疚、绝望、孤独、愤怒、自我仇恨和不安)与自杀思维严重程度之间的关联强于没有 BPD 的患者。这一发现对临床环境中的风险评估和干预具有重要意义:对于给定程度的报告负面情绪,BPD 患者比没有 BPD 的患者经历更多的自杀意念。需要进一步研究以阐明这种效应的机制。