Grayzel A I, Marcus R, Stern R, Winchester R J
Arthritis Rheum. 1977 Apr;20(3):887-94. doi: 10.1002/art.1780200319.
Two adult patients with hypogammaglobulinemia and chronic synovitis were studied. Synovial tissue and fluid were examined by histologic, virologic, and immunologic methods. The synovium lacked characteristic histologic features of rheumatoid arthritis, and B lymphocytes were absent from the synovial tissue, fluid, and peripheral blood. These 2 patients may represent a form of chronic synovitis produced in the absence of any B lymphocyte response.
对两名患有低丙种球蛋白血症和慢性滑膜炎的成年患者进行了研究。通过组织学、病毒学和免疫学方法对滑膜组织和滑液进行了检查。滑膜缺乏类风湿性关节炎的特征性组织学特征，滑膜组织、滑液和外周血中均未发现B淋巴细胞。这两名患者可能代表了一种在没有任何B淋巴细胞反应的情况下产生的慢性滑膜炎形式。
