Département de Psychologie, Université de Montréal, Montréal, QC, Canada.
Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), CIUSSS du Centre-Sud-de-l'Île-de-Montréal, Montréal, QC, Canada.
J Alzheimers Dis. 2018;65(2):519-542. doi: 10.3233/JAD-170881.
The language changes that occur over the course of Alzheimer's disease (AD) can impact communication abilities and have profound functional consequences. Picture description tasks can be used to approximate everyday communication abilities of AD patients. As various methods and variables have been studied over the years, current knowledge about the most affected features of AD discourse in the context of picture descriptions is difficult to summarize. This systematic review aims to provide researchers with an overview of the most common areas of impairment in AD discourse as they appear in picture description tasks. Based on the 44 articles fulfilling inclusion criteria, our findings reflect a multidimensional pattern of changes in the production (speech rate), syntactic (length of utterance), lexical (word-frequency and use of pronouns), fluency (repetitions and word-finding difficulties), semantic (information units), and discourse (efficiency) domains. We discuss our findings in the light of current research and point to potential scientific and clinical uses of picture description tasks in the context of AD.
在阿尔茨海默病（AD）发展过程中发生的语言变化会影响交流能力，并产生深远的功能后果。图片描述任务可用于近似 AD 患者的日常交流能力。多年来，人们研究了各种方法和变量，因此，关于在图片描述背景下 AD 话语受影响最严重的特征的现有知识难以概括。本系统综述旨在为研究人员提供 AD 话语在图片描述任务中最常见的损伤区域概述。根据符合纳入标准的 44 篇文章，我们的研究结果反映了在言语产生（语速）、句法（话语长度）、词汇（词汇频率和代词使用）、流畅性（重复和找词困难）、语义（信息单元）和语篇（效率）领域的多维变化模式。我们根据当前研究讨论了我们的研究结果，并指出了在 AD 背景下图片描述任务在科学和临床方面的潜在用途。
