Trakimas Danielle R, Kempfle Judith S, Reinshagen Katherine L, Lee Daniel J, Kozin Elliott D, Remenschneider Aaron K
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA, USA; Department of Otolaryngology, Harvard Medical School, Boston, MA, USA; University of Massachusetts Medical School, Worcester, MA, USA.
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA, USA; Department of Otolaryngology, Harvard Medical School, Boston, MA, USA; Department of Otolaryngology, University Tübingen Medical Center, Elfriede-Aulhorn-Str. 5, 72076 Tübingen, Germany.
Am J Otolaryngol. 2018 Nov-Dec;39(6):731-736. doi: 10.1016/j.amjoto.2018.07.024. Epub 2018 Aug 1.
Effective operative approaches for the treatment of refractory vertigo in Meniere's disease are invasive. Vestibular neurectomy can preserve hearing and has been shown to be effective; however, current approaches require an extensive craniotomy. Transcanal endoscopic approaches to the internal auditory canal (IAC) with cochlear preservation have been recently described and may offer a minimally invasive approach to selectively sectioning the distal vestibular nerves while preserving residual hearing.
Three cadaveric human heads were imaged using high resolution computed tomography (CT). Anatomic analysis of preoperative CT scans showed adequate diameters (>3 mm) of the infracochlear surgical corridor for access to the IAC. A transcanal endoscopic approach was attempted to section the vestibular nerve. Post-operative CT scans were assessed to define the operative tract, determine cochlear preservation and assess cochlear and facial nerve preservation.
Transcanal endoscopic approach was successfully performed (n = 3) using 3 mm-diameter, 14 cm-length 0°, 30°, and 45° endoscopes and microsurgical drills. In all cases the tympanomeatal flap and ossicular chain remained intact. Internal auditory canalotomy was performed using angled instruments and confirmed in real time via lateral skull base navigation. The vestibular nerves were readily identified and sectioned with preservation of the facial and cochlear nerves. Post-procedure CT showed no violation of the cochlea.
A transcanal, infracochlear approach to the IAC may permit a minimally invasive approach to distal vestibular neurectomy in cadavers with appropriate anatomy.
治疗梅尼埃病难治性眩晕的有效手术方法具有侵袭性。前庭神经切断术可保留听力且已被证明有效;然而,目前的方法需要广泛的开颅手术。最近描述了经耳道内镜进入内耳道(IAC)并保留耳蜗的方法,这可能提供一种微创方法,在保留残余听力的同时选择性切断远端前庭神经。
使用高分辨率计算机断层扫描(CT)对三个尸体人头进行成像。术前CT扫描的解剖分析显示,耳蜗下手术通道直径足够(>3毫米),可进入IAC。尝试采用经耳道内镜方法切断前庭神经。评估术后CT扫描以确定手术路径、确定耳蜗保留情况并评估耳蜗和面神经保留情况。
使用直径3毫米、长度14厘米的0°、30°和45°内镜及显微外科钻成功实施了经耳道内镜手术(n = 3)。在所有病例中,鼓膜瓣和听骨链均保持完整。使用成角器械进行内耳道切开术,并通过外侧颅底导航实时确认。前庭神经很容易识别并切断,同时保留面神经和耳蜗神经。术后CT显示耳蜗未受侵犯。
对于解剖结构合适的尸体,经耳道、耳蜗下进入IAC的方法可能允许对远端前庭神经切断术采用微创方法。