体外受精/卵胞浆内单精子注射失败且精子 DNA 碎片化增加的夫妇在下一个周期是否应该使用睾丸精子？
Should A Couple with Failed In Vitro Fertilization/Intracytoplasmic Sperm Injection and Increased Sperm DNA Fragmentation Use Testicular Sperm for the Next Cycle?
机构信息
Department of Urology, Weill Cornell Medicine, New York, NY, USA.
Department of Urology, Weill Cornell Medicine, New York, NY, USA.
出版信息
Eur Urol Focus. 2018 Apr;4(3):299-300. doi: 10.1016/j.euf.2018.08.002. Epub 2018 Aug 10.
PMID:30104168
Abstract
Limited observational data purporting a benefit of testicular sperm for intracytoplasmic sperm injection failure do not provide sufficient evidence. The first step is to reduce sperm DNA fragmentation in ejaculated sperm through lifestyle modifications, antioxidant therapy, or treatment of underlying abnormalities such as infection or varicocele.
摘要
有限的观察性数据表明睾丸精子对卵胞浆内单精子注射失败有益，但这些数据并没有提供足够的证据。首先，通过生活方式的改变、抗氧化治疗或治疗感染或精索静脉曲张等潜在异常，来降低射出精液中的精子 DNA 碎片。
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