Masrouha Karim Z, Callaghan John J, Morcuende José A
Department of Orthopedic Surgery, New York University Langone Orthopedic Hospital, New York, NY, U.S.A.
Department of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, IA, U.S.A.
Iowa Orthop J. 2018;38:197-202.
Patients with Legg-Calvé-Perthes Syndrome (LCPS) are at an increased risk for developing osteoarthritis of the hip and undergoing total hip arthroplasty (THA) at an early age. Importantly, this younger age may put them at a higher risk for failure and revision surgery. The purpose of the study was to assess the clinical and radiographic outcomes as well as implant failure rate and risk for revision surgery at an average 20 years follow up.
Data from LCPS patients treated with THA were collected including age, gender, operative date, revision date, as well as reason for and type of revision. Living patients filled the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaires at the time of last follow-up. Radiographs were evaluated for lucencies, debonding, loosening, osteolysis, wear, heterotopic ossification and sclerosis.
Nineteen patients (20 hips) treated with THA were followed-up for a mean of 18.3 years (range, 10.1 - 36.2 years). Radiographic evidence of lucency of the acetabular component was seen in 70% of the patients and femoral cortical hypertrophy in 85% at last follow-up. The rate of revision for any reason was 35%, mostly due to aseptic acetabular loosening.
Our findings support the use of THA for the treatment of OA in patients with LCPS, bearing in mind the potentially lower survival rate at 20 years as compared those treated with THA for primary OA. Further studies are needed to identify the possible causes of the high rate of cortical hypertrophy seen in this patient population.Level of Evidence: IV Therapeutic.
患有Legg-Calvé-Perthes综合征(LCPS)的患者发生髋关节骨关节炎并在年轻时接受全髋关节置换术(THA)的风险增加。重要的是,这个较年轻的年龄可能使他们面临更高的失败风险和翻修手术风险。本研究的目的是评估平均20年随访时的临床和影像学结果以及植入物失败率和翻修手术风险。
收集接受THA治疗的LCPS患者的数据,包括年龄、性别、手术日期、翻修日期以及翻修原因和类型。在世患者在最后一次随访时填写西安大略和麦克马斯特大学骨关节炎指数(WOMAC)问卷。对X线片进行评估,观察透亮区、脱粘、松动、骨溶解、磨损、异位骨化和硬化情况。
19例接受THA治疗的患者(20髋)平均随访18.3年(范围10.1 - 36.2年)。在最后一次随访时,70%的患者可见髋臼组件透亮的影像学证据,85%的患者可见股骨皮质肥大。任何原因导致的翻修率为35%,主要原因是无菌性髋臼松动。
我们的研究结果支持使用THA治疗LCPS患者的骨关节炎,同时要记住与原发性骨关节炎接受THA治疗的患者相比,20年时的生存率可能较低。需要进一步研究以确定该患者群体中观察到的高皮质肥大率的可能原因。证据级别:IV 治疗性。