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患者对青蒿素联合疗法治疗的认知及其对患者依从性的影响。

Patients' Knowledge of Artemisinin-Based Combination Therapy Treatment and Its Impact on Patient Adherence.

作者信息

Afaya Agani, Salia Solomon Mohammed, Adatara Peter, Afaya Richard Adongo, Suglo Solomon, Japiong Milipaak

机构信息

School of Nursing and Midwifery, University of Health and Allied Health Sciences, Ho, Ghana.

Department of Nursing, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

出版信息

J Trop Med. 2018 Jul 18;2018:7465254. doi: 10.1155/2018/7465254. eCollection 2018.

Abstract

Despite increased support from government and other stakeholders for malaria control over the past decade, malaria burden remains high in many endemic countries, particularly in Sub-Saharan Africa. This study aimed to assess patients' knowledge of antimalarial treatment (ACT) and its association with patient adherence. A descriptive cross-sectional study design was employed in this study. Data were collected from April to May 2017. Both descriptive and inferential statistics in the form of frequencies, percentages, mean values, standard deviations, and Pearson's chi-square test were generated by use of Microsoft excel spreadsheet and IBM Statistical Package for Social Sciences (SPSS) version 23. The average age of the respondents surveyed for this study was 42.27 ± 11.09. Adherence level to ACT was 47%. The results showed that there was a significant association between respondents' knowledge of the efficacy of antimalarial medication ( 0.003), benefits of completing antimalarial treatment course ( 0.001), and consequences of not completing the doses of antimalarial medication prescribed ( 0.002) and adherence to ACT. This study then recommends that improving patients' knowledge regarding the efficacy, benefits of completing ACT, and consequences of not completing ACT treatment may improve the likelihood of patients adhering fully to ACT.

摘要

尽管在过去十年中政府和其他利益相关者对疟疾控制的支持有所增加,但许多疟疾流行国家的疟疾负担仍然很高,特别是在撒哈拉以南非洲。本研究旨在评估患者对抗疟治疗(ACT)的了解及其与患者依从性的关联。本研究采用描述性横断面研究设计。数据于2017年4月至5月收集。使用Microsoft excel电子表格和IBM社会科学统计软件包(SPSS)23版生成了频率、百分比、平均值、标准差和Pearson卡方检验等描述性和推断性统计数据。本研究调查的受访者平均年龄为42.27±11.09。ACT的依从水平为47%。结果表明,受访者对抗疟药物疗效的了解(0.003)、完成抗疟治疗疗程的益处(0.001)以及未完成规定抗疟药物剂量的后果(0.002)与ACT依从性之间存在显著关联。本研究随后建议,提高患者对抗疟治疗疗效、完成ACT的益处以及未完成ACT治疗后果的认识,可能会提高患者完全依从ACT的可能性。

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