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通过胶片测量对新型电子近距离放射治疗串联源模型进行研究。

Investigation of a source model for a new electronic brachytherapy tandem by film measurement.

作者信息

Martin Elijah, Sowards Keith, Wang Brian

机构信息

Department of Radiation Oncology, University of Louisville, Louisville, KY, USA.

出版信息

J Appl Clin Med Phys. 2018 Sep;19(5):640-650. doi: 10.1002/acm2.12440. Epub 2018 Aug 13.

Abstract

PURPOSE

To investigate the accuracy of a vendor-supplied source model for a new Xoft Axxent 0-degree titanium tandem by film measurement.

METHODS

We measured the anisotropy factors at varying distances and angles from the tandem in water using radiochromic film (Gafchromic EBT3) and an Epson Perfection v750 desktop flatbed scanner (US Epson, Long Beach, CA). A 0-degree tandem was placed vertically in a water phantom. Four pieces of film, each at varying depths, were positioned orthogonal to the longitudinal axis of the tandem for azimuthal anisotropy measurements. Polar anisotropy measurements were taken with the film aligned parallel to the tandem. An absolute dose calibration for the film was verified with a PTW 34013 Soft X-Ray Chamber. The film measurements were analyzed using different color channels. The measured polar anisotropy for varying source positions was compared to the vendor's data. Azimuthal anisotropy was measured as a function of the radius and angle, and normalized to the mean value over all angles at the specified radius.

RESULTS

The azimuthal anisotropy of the tandem and source was found to be consistent for different positions along the tandem's longitudinal axis and at varying distances from the tandem. Absolute dose using a calibrated parallel plate chamber showed agreement to within 2% of expected TPS values. The custom tandem, which has a thicker tip than the wall, was attenuating the 50 kV photons more than expected, at the angles where the photons had more wall material to traverse. This discrepancy was verified at different distances from the tandem and with different measurement techniques. As distance increased, anisotropy values had better agreement.

CONCLUSIONS

We quantified the agreement between the measured and provided anisotropy factors for a new Xoft Axxent 0-degree titanium tandem. Radiochromic film response at low kV energy was also investigated. Our results showed that vendor-supplied TG-43 values were appropriate for clinical use at majority of the angles. A rigorous quality assurance method for new electronic brachytherapy sources and applicators, along with complete knowledge of all dosimetric measuring tools, should be implemented for all parts of the verification and commissioning process.

摘要

目的

通过胶片测量研究供应商提供的用于新型Xoft Axxent 0度钛制施源器的源模型的准确性。

方法

我们使用放射变色胶片(Gafchromic EBT3)和爱普生Perfection v750桌面平板扫描仪(美国爱普生公司,加利福尼亚州长滩)在水中测量了距施源器不同距离和角度处的各向异性因子。将一个0度施源器垂直放置在水模体中。在不同深度放置四张胶片,使其与施源器的纵轴正交,用于方位各向异性测量。胶片与施源器平行排列时进行极向各向异性测量。使用PTW 34013软X射线腔室对胶片进行绝对剂量校准。使用不同的颜色通道分析胶片测量结果。将不同源位置处测得的极向各向异性与供应商的数据进行比较。测量方位各向异性作为半径和角度的函数,并将其归一化为指定半径处所有角度的平均值。

结果

发现施源器和源的方位各向异性在施源器纵轴上的不同位置以及距施源器不同距离处是一致的。使用校准后的平行板腔室测得的绝对剂量与预期的TPS值相差在2%以内。定制的施源器尖端比管壁厚,在光子需要穿过更多管壁材料的角度,其对50 kV光子的衰减比预期的更多。在距施源器不同距离处以及使用不同测量技术时都验证了这种差异。随着距离增加,各向异性值的一致性更好。

结论

我们对新型Xoft Axxent 0度钛制施源器测量的和供应商提供的各向异性因子之间的一致性进行了量化。还研究了放射变色胶片在低kV能量下的响应。我们的结果表明,供应商提供的TG-43值在大多数角度适用于临床。对于新的电子近距离放射治疗源和施源器,应在验证和调试过程的所有环节实施严格的质量保证方法,并全面了解所有剂量测量工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acca/6123150/1c8d1035bda8/ACM2-19-640-g010.jpg

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