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父母对女儿死后卵巢组织的使用:伦理维度。

Parents' posthumous use of daughter's ovarian tissue: Ethical dimensions.

机构信息

Bioethics Programs, School of Public Health, University of Montreal, Montreal, Quebec, Canada.

出版信息

Bioethics. 2019 Jan;33(1):82-90. doi: 10.1111/bioe.12491. Epub 2018 Aug 14.

DOI:10.1111/bioe.12491
PMID:30106178
Abstract

In recent years, progress in cancer treatment has greatly increased the chances of recovery. Yet, treatment may have irreversible effects on patients' fertility. In order to protect future fertility, preservation of ovarian tissue may be offered today even to very young girls, involving a surgical procedure that may be performed by minimally invasive laparoscopy, under general anesthesia. However, in the tragic event of a girl's death, questions may arise regarding the possible use of the preserved ovarian tissue by her parents. Should posthumous reproductive use of ovarian tissue without the girl's prior consent (due to her young age) be considered a violation of her rights? On the other hand, can it be argued that it is in the interest of a child who died young to leave a genetic trace through posthumous reproduction, because genetic continuity is in the interest of every human being? After presenting the relevant clinical facts, we explore the ethical dimensions of this possible practice through an analysis of the interests of the deceased, her parents, and the child that may be born posthumously.

摘要

近年来,癌症治疗的进展大大提高了患者康复的机会。然而,治疗可能对患者的生育能力产生不可逆转的影响。为了保护未来的生育能力,即使是非常年轻的女孩,今天也可能提供卵巢组织保存,这涉及到一个手术过程,可以通过全身麻醉下的微创腹腔镜进行。然而,在女孩不幸去世的情况下,可能会出现关于其父母可能使用保存的卵巢组织的问题。未经女孩事先同意(由于她年龄较小)进行死后生殖性使用卵巢组织是否应被视为侵犯其权利?另一方面,是否可以认为,通过死后繁殖为早逝的孩子留下遗传痕迹符合其利益,因为遗传连续性符合每个人的利益?在介绍相关临床事实之后,我们通过分析死者、她的父母和可能死后出生的孩子的利益,探讨了这种可能做法的伦理维度。

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1
Parents' posthumous use of daughter's ovarian tissue: Ethical dimensions.父母对女儿死后卵巢组织的使用:伦理维度。
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引用本文的文献

1
Ovarian tissue cryopreservation: a narrative review on cryopreservation and transplantation techniques, and the clinical outcomes.卵巢组织冷冻保存:关于冷冻保存和移植技术以及临床结果的叙述性综述
Ther Adv Reprod Health. 2025 Jun 1;19:26334941251340517. doi: 10.1177/26334941251340517. eCollection 2025 Jan-Dec.
2
Mapping ethical, legal, and social implications (ELSI) of fertility preservation.绘制生育力保存的伦理、法律和社会影响(ELSI)图谱。
J Assist Reprod Genet. 2024 Sep;41(9):2495-2514. doi: 10.1007/s10815-024-03210-w. Epub 2024 Aug 14.
3
Ethical, legal, social, and policy issues of ovarian tissue cryopreservation in prepubertal girls: a critical interpretive review.
青春期前女孩卵巢组织冷冻保存的伦理、法律、社会和政策问题:批判性解释性综述。
J Assist Reprod Genet. 2024 Apr;41(4):999-1026. doi: 10.1007/s10815-024-03059-z. Epub 2024 Mar 2.
4
Keeping it in the family: reproduction beyond genetic parenthood.延续家族:超越亲生父母的生育方式。
J Med Ethics. 2025 Jan 23;51(2):111-114. doi: 10.1136/jme-2023-109814.