Schenk P
Acta Otolaryngol. 1986 Mar-Apr;101(3-4):295-8. doi: 10.3109/00016488609132841.
The ultrastructure of Kaposi's sarcoma (KS) of the oral mucosa in patients with acquired immune deficiency syndrome (AIDS) was examined electron microscopically. The tumour consisted of pleomorphic vascular endothelial structures and spindle cell formations. The KS cells contained characteristically numerous multivesicular bodies, a large number of tubuloreticular structures and abundant Weibel-Palade bodies in their cytoplasm. Virus particles, 100-120 nm in diameter, were observed budding from the plasma membrane or as free particles already separated from the plasma membrane. Many mature virions manifested a dense cylindrical-shaped core. These virus particles and the human T-cell lymphotropic retroviruses subgroup HTLV-III are ultrastructurally identical. This report is based on recent immunological research.
对获得性免疫缺陷综合征（AIDS）患者口腔黏膜卡波西肉瘤（KS）的超微结构进行了电镜检查。肿瘤由多形性血管内皮结构和梭形细胞构成。KS细胞的细胞质中特征性地含有大量多囊泡体、大量管状网状结构和丰富的魏-帕小体。观察到直径为100 - 120纳米的病毒颗粒从质膜出芽，或作为已与质膜分离的游离颗粒。许多成熟病毒粒子呈现出致密的圆柱形核心。这些病毒颗粒与人类嗜T细胞逆转录病毒Ⅲ型亚组在超微结构上是相同的。本报告基于近期的免疫学研究。
