Kuntz A A, Gelderblom H R, Winkel T, Reichart P A
Department of Oral Surgery, Free University of Berlin, West Germany.
J Oral Pathol. 1987 Aug;16(7):372-9. doi: 10.1111/j.1600-0714.1987.tb00711.x.
Ten biopsies of oral Kaposi's sarcoma were examined histologically and ultrastructurally. Histologically, early and late tumor stages could be differentiated. On the ultrastructural level, endothelial-like and spindle-shaped tumor cells were revealed. Tumor cells associated with vessel-like spaces showed partly interrupted basal membranes, Weibel-Palade bodies, desmosomes and tight-junctions, while spindle-shaped cells lacked these ultrastructural features of endothelial cells. Within the cytoplasm of endothelial-like cells, aggregates of tubular structures were observed. Histological and ultrastructural findings in oral Kaposi sarcoma are comparable to those of such other organs as skin and intestines. The ultrastructural findings indicate an endothelial origin, at least of endothelial-like tumor cells.
对10例口腔卡波西肉瘤活检标本进行了组织学和超微结构检查。在组织学上，可以区分肿瘤的早期和晚期阶段。在超微结构水平上，发现了内皮样和梭形肿瘤细胞。与血管样间隙相关的肿瘤细胞显示部分中断的基底膜、魏-帕小体、桥粒和紧密连接，而梭形细胞缺乏内皮细胞的这些超微结构特征。在内皮样细胞的细胞质中，观察到管状结构聚集体。口腔卡波西肉瘤的组织学和超微结构发现与皮肤和肠道等其他器官的发现相似。超微结构发现表明，至少内皮样肿瘤细胞起源于内皮细胞。
