Medstar Georgetown University Hospital, Department of Neurosurgery, Pasquerilla Healthcare Center (PHC), Washington, District of Columbia.
Georgetown University School of Medicine, Washington, District of Columbia.
Oper Neurosurg (Hagerstown). 2019 Jun 1;16(6):750-755. doi: 10.1093/ons/opy221.
Surgical site infection (SSI) in spinal surgery contributes to significant morbidity and healthcare resource utilization. Few studies have directly compared the rate of minimally invasive surgery (MIS) SSI with open surgery.
To investigate whether MIS techniques had a lower SSI rate in degenerative lumbar procedures as compared with traditional open techniques.
A single-center, retrospective review of a prospectively collected database was queried from January 2013 to 2016 for adult patients who underwent lumbar decompression and/or instrumented fusion for which the surgical indication involved degenerative disease. The SSI rate was determined for all procedures as well as in the open and minimally invasive groups. Risk factors associated with SSI were also reviewed for each patient.
A total of 1442 lumbar spinal procedures were performed during this time period. Of these, there were 961 MIS and 481 open (67% vs 33%, respectively). The overall SSI rate was 1.5% (21/1442). The surgical site infection rate for MIS was less than open techniques (0.5% vs 3.3%; P = .0003). For decompression only, the infection rate for MIS and open was 0.4% vs 3.9% (P = .04), and for decompression with fusion it was 0.7% vs 2.6%, respectively (P = .68).
Our study demonstrates a significant 7-fold reduction in SSIs when comparing MIS with open surgery. This significance was also demonstrated with a 10-fold reduction for procedures involving decompression alone. Procedures that require fusion as well as decompression showed a trend towards a decreased infection rate that did not reach clinical significance.
脊柱手术部位感染(SSI)会导致显著的发病率和医疗资源利用。很少有研究直接比较微创(MIS)SSI 与开放手术的发生率。
调查与传统开放技术相比,MIS 技术在退行性腰椎手术中是否具有较低的 SSI 发生率。
对 2013 年 1 月至 2016 年期间前瞻性收集的数据库进行了单中心回顾性分析,纳入接受腰椎减压和/或器械融合的成人患者,手术适应证为退行性疾病。确定了所有手术以及开放组和微创组的 SSI 发生率。还回顾了每位患者与 SSI 相关的危险因素。
在此期间共进行了 1442 例腰椎脊柱手术。其中,MIS 组 961 例,开放组 481 例(分别为 67%和 33%)。总的 SSI 发生率为 1.5%(21/1442)。MIS 的手术部位感染率低于开放技术(0.5%对 3.3%;P=0.0003)。仅减压时,MIS 和开放的感染率分别为 0.4%和 3.9%(P=0.04),减压融合时分别为 0.7%和 2.6%(P=0.68)。
我们的研究表明,与开放手术相比,MIS 可显著降低 SSI 发生率。这一意义在单独减压手术中也得到了 10 倍的证明。需要融合和减压的手术显示出感染率降低的趋势,但未达到临床意义。