Francomano C A, Kazazian H H
Annu Rev Med. 1986;37:377-95. doi: 10.1146/annurev.me.37.020186.002113.
Recombinant DNA technology has applications in the analysis of an ever-increasing number of genetic disorders. This review discusses the basic genetic principles underlying recombinant DNA techniques, the general approach to analyzing genetic disorders using these methods, and finally the practical applications of DNA analysis in genetic disease.
