Bierwolf D
Arch Geschwulstforsch. 1986;56(2):89-97.
A short overview of the history of tumor virology is given with respect to the special data of research in this field done by Arnold Graffi and his coworkers. The theory of viral etiology of tumors during the 75 years since its inauguration had to be proven by scientists fighting for the idea of viral agents being the cause of several types of cancer in animals and man. Today this theory is accepted; a series of human tumors is known as induced by viruses, too. Moreover, tumor viruses have increased our knowledge of mechanisms of malignant transformation and the discovery of one genes has opened new possibilities for analysis of the process of cancerogenesis.
本文结合阿诺德·格拉菲及其同事在该领域的特殊研究数据,对肿瘤病毒学的历史作了简要概述。自肿瘤病毒病因学理论创立75年来,一直有科学家致力于证明病毒因子是导致动物和人类多种癌症的原因。如今这一理论已被接受;一系列人类肿瘤也被认为是由病毒引起的。此外,肿瘤病毒增进了我们对恶性转化机制的了解,一个基因的发现为癌症发生过程的分析开辟了新的可能性。