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评估Epworth嗜睡量表在预测病态肥胖患者阻塞性睡眠呼吸暂停中的作用并提高其效用。

Evaluation of Epworth Sleepiness Scale to Predict Obstructive Sleep Apnea in Morbidly Obese Patients and Increasing Its Utility.

作者信息

Singla Vitish, Gattu Tharun, Aggarwal Sandeep, Bhambri Amit, Agarwal Samagra

机构信息

1 Department of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS) , New Delhi, India .

2 Department of Internal Medicine, All India Institute of Medical Sciences (AIIMS) , New Delhi, India .

出版信息

J Laparoendosc Adv Surg Tech A. 2019 Mar;29(3):298-302. doi: 10.1089/lap.2018.0329. Epub 2018 Aug 15.

Abstract

INTRODUCTION

Studies have shown that Epworth sleepiness scale (ESS) is not a good tool to predict obstructive sleep apnea (OSA). However, data regarding the accuracy of ESS in the prediction of OSA among morbidly obese patients are scarce.

METHODS

The study involved a retrospective review of the charts of the consecutive patients who underwent bariatric surgery at a tertiary care teaching hospital. All the patients underwent polysomnography (PSG) and undertook the ESS questionnaire. The sensitivity and specificity of ESS were calculated based on its correlation with the PSG findings. Furthermore, a new score was devised to improve the utility of ESS to predict OSA.

RESULTS

A total of 232 consecutive patients from January 2014 to July 2017 were included in the study. The mean age and body mass index (BMI) were 40.5 ± 11.8 years and 47.6 ± 7.3 kg/m, respectively. Among the 162 patients who had an ESS <10, 57.4% had moderate-to-severe OSA. The sensitivity of ESS to predict moderate-to-severe OSA was found to be 38.8% and the positive predictive value was 84.2% (positive likelihood ratio 2.82, 95% confidence interval = 1.57-5.06). A predictive score was identified as 0.031Age (years) +0.039BMI (kg/m) + 0.038ESS + Gender (1 for male, 0 for female). The score had a sensitivity of 80% at a cutoff of 3.3.

CONCLUSIONS

Among the morbidly obese, ESS is a poor predictor of OSA. Its utility as a tool for prediction of moderate-to-severe OSA can be improved by use of a new formula incorporating age, gender, and BMI beside ESS.

摘要

引言

研究表明,爱泼沃斯思睡量表(ESS)并非预测阻塞性睡眠呼吸暂停(OSA)的良好工具。然而,关于ESS在病态肥胖患者中预测OSA准确性的数据却很匮乏。

方法

本研究对一家三级护理教学医院中连续接受减肥手术患者的病历进行回顾性分析。所有患者均接受了多导睡眠图(PSG)检查并填写了ESS问卷。基于ESS与PSG检查结果的相关性计算其敏感性和特异性。此外,还设计了一个新的评分系统以提高ESS预测OSA的效用。

结果

2014年1月至2017年7月期间共有232例连续患者纳入本研究。平均年龄和体重指数(BMI)分别为40.5±11.8岁和47.6±7.3kg/m²。在ESS<10的162例患者中,57.4%患有中重度OSA。发现ESS预测中重度OSA的敏感性为38.8%,阳性预测值为84.2%(阳性似然比2.82,95%置信区间=1.57 - 5.06)。确定的预测评分为0.031×年龄(岁)+0.039×BMI(kg/m²)+0.038×ESS+性别(男性为1,女性为0)。该评分在截断值为3.3时敏感性为80%。

结论

在病态肥胖患者中,ESS对OSA的预测能力较差。通过使用一个除ESS外还纳入年龄、性别和BMI的新公式,可提高其作为预测中重度OSA工具的效用。

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