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肥胖症手术前阻塞性睡眠呼吸暂停的流行率和预测-四个睡眠问卷的性别特异性表现。

Prevalence and Prediction of Obstructive Sleep Apnea Prior to Bariatric Surgery-Gender-Specific Performance of Four Sleep Questionnaires.

机构信息

Department of Pulmonary Medicine, Inselspital, University Hospital and University of Bern, Freiburgstrasse 4, 3010, Bern, Switzerland.

Department of Pneumology and Sleep Medicine, Kantonsspital St. Gallen, Rorschacherstrasse 95, 9000, St. Gallen, Switzerland.

出版信息

Obes Surg. 2018 Sep;28(9):2720-2726. doi: 10.1007/s11695-018-3222-z.

DOI:10.1007/s11695-018-3222-z
PMID:29616468
Abstract

PURPOSE

Bariatric surgery (BS) is a treatment option for morbid obesity leading to substantial and sustained weight loss in adults. As obstructive sleep apnea (OSA) is highly prevalent in obese subjects and may increase the perioperative risk, screening for OSA is recommended prior to BS. In clinical routine, BS is performed more frequently in women. Therefore, we sought to assess the gender-specific performance of four sleep questionnaires (Epworth Sleepiness Scale (ESS), Fatigue Severity Scale (FSS), STOPBang, and NoSAS) to predict moderate to severe OSA in the morbidly obese population.

MATERIAL AND METHODS

We applied all four questionnaires to patients scheduled for BS with polygraphic OSA screening at our institution between 2012 and 2015 and performed gender-specific sensitivity analyses.

RESULTS

We included 251 bariatric patients (76% female, median age 39 years, median BMI 42.0 kg/m). OSA (AHI > 5/h; AHI > 15/h) was present in 43% (females 35%, males 68%; p < 0.001) and 21% (females 13%, males 45%; p < 0.001). STOPBang and NoSAS performed markedly better than ESS and FSS. With the exception of the ESS, all sleep questionnaires allowed better OSA prediction in women than in men.

CONCLUSION

In obese patients scheduled for BS, a gender-specific difference was observed in the performance of the evaluated OSA screening questionnaires. This needs to be considered when these questionnaires are used. Our results underline the need for better gender-specific OSA screening algorithms in morbidly obese patients.

摘要

目的

减重手术(BS)是治疗病态肥胖的一种方法,可导致成年人显著且持续的体重减轻。由于阻塞性睡眠呼吸暂停(OSA)在肥胖人群中高发,并可能增加围手术期风险,因此建议在进行 BS 前进行 OSA 筛查。在临床常规中,BS 在女性中更为常见。因此,我们旨在评估四项睡眠问卷(Epworth 嗜睡量表(ESS)、疲劳严重程度量表(FSS)、STOPBang 和 NoSAS)在预测病态肥胖人群中中重度 OSA 方面的性别特异性表现。

材料和方法

我们对 2012 年至 2015 年在我院接受多导睡眠图 OSA 筛查并计划进行 BS 的患者应用了这四项问卷,并进行了性别特异性敏感性分析。

结果

我们纳入了 251 名接受 BS 的肥胖患者(76%为女性,中位年龄 39 岁,中位 BMI 为 42.0 kg/m²)。存在 OSA(AHI > 5/h;AHI > 15/h)的患者占 43%(女性占 35%,男性占 68%;p < 0.001)和 21%(女性占 13%,男性占 45%;p < 0.001)。STOPBang 和 NoSAS 的表现明显优于 ESS 和 FSS。除了 ESS 之外,所有睡眠问卷在女性中的 OSA 预测效果均优于男性。

结论

在计划进行 BS 的肥胖患者中,评估的 OSA 筛查问卷在性能方面存在性别差异。在使用这些问卷时需要考虑到这一点。我们的结果强调了在病态肥胖患者中需要更好的性别特异性 OSA 筛查算法。

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