Lyu Chun-Yan, Lyu Shao-Wa, Li Guo-Yu, Kuang Hai-Xue
Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Harbin University of Commerce, Harbin 150076, China.
Zhongguo Zhong Yao Za Zhi. 2018 Jul;43(14):2892-2898. doi: 10.19540/j.cnki.cjcmm.20180327.007.
The theory of medicinal properties of traditional Chinese medicine (TCM) is one of the core theories of TCM, which is an important basis for guiding the clinical application of TCM and the key supporting point for the modernization of TCM. How to study the modernization of TCM under the guidance of traditional Chinese medicine theory has become a great challenge for modern researchers. Currently, the researches in TCM mainly focus on chemical studies such as on active ingredients and effective components, lacking the guidance of traditional Chinese medicine theory, and losing the inherent characteristics of TCM. Therefore, the combination of the theory of TCM and the modernization of TCM and the establishment of research mode that is in line with the characteristics of modernization of traditional Chinese medicine under guidance by the theory of medicinal properties of TCM shall be the top priority in modern Chinese medicine research. The property and flavor of TCM are closely related to its chemical compositions, and also have certain regularity. The researches on the chemical components of TCM, systematic design of property and flavor, as well as the separation and combination of TCM property and flavor are beneficial to the overall analysis of the characteristics of TCM, showing great significance to inherit and carry forward TCM. The pharmacological effects about separation and combination methods based on TCM property and flavor were reviewed in this study, providing theoretical reference for the development of new drugs and the application of TCM.
中药药性理论是中医的核心理论之一，是指导中医临床应用的重要依据，也是中医现代化的关键支撑点。如何在中医理论指导下开展中医现代化研究，已成为现代研究者面临的巨大挑战。目前，中医研究主要集中在活性成分、有效成分等化学研究方面，缺乏中医理论的指导，丧失了中医的固有特色。因此，将中医理论与中医现代化相结合，构建在中药药性理论指导下符合中医现代化特点的研究模式，应是现代中医研究的重中之重。中药的性味与其化学成分密切相关，且具有一定规律性。开展中药化学成分、性味的系统设计以及中药性味的拆分与合组研究，有助于全面剖析中药特性，对传承和弘扬中医药具有重要意义。本研究对基于中药性味的拆分与合组方法的药理效应进行综述，为新药研发及中药应用提供理论参考。
