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α,β-亚甲基ATP对未成熟大鼠基底动脉中去甲肾上腺素诱发的去极化（γ-肾上腺素能受体反应）及ATP的影响。

The effect of alpha, beta-methylene ATP on the depolarization evoked by noradrenaline (gamma-adrenoceptor response) and ATP in the immature rat basilar artery.

作者信息

Byrne N G, Large W A

出版信息

Br J Pharmacol. 1986 May;88(1):6-8. doi: 10.1111/j.1476-5381.1986.tb09464.x.

DOI:10.1111/j.1476-5381.1986.tb09464.x
PMID:3011173
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1917104/
Abstract

Depolarizations evoked by noradrenaline that were resistant to alpha- and beta-adrenoceptor antagonists were recorded in the rat basilar artery. These gamma-adrenoceptor-mediated responses and the depolarizations to adenosine triphosphate (ATP) were blocked by pretreatment of the tissue with alpha, beta-methylene ATP. These data are discussed with respect to the selectivity of alpha, beta-methylene ATP.

摘要

在大鼠基底动脉中记录到了去甲肾上腺素诱发的去极化反应，该反应对α和β肾上腺素能受体拮抗剂具有抗性。这些γ肾上腺素能受体介导的反应以及对三磷酸腺苷（ATP）的去极化反应，在组织用α,β-亚甲基ATP预处理后被阻断。针对α,β-亚甲基ATP的选择性对这些数据进行了讨论。

相似文献

1
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本文引用的文献

1
Evidence that ATP acts as a co-transmitter with noradrenaline in sympathetic nerves supplying the guinea-pig vas deferens.有证据表明，在支配豚鼠输精管的交感神经中，三磷酸腺苷（ATP）作为去甲肾上腺素的共递质发挥作用。
Eur J Pharmacol. 1983 Aug 19;92(1-2):161-3. doi: 10.1016/0014-2999(83)90126-7.
2
Inhibition of excitatory junction potentials in guinea-pig vas deferens by alpha, beta-methylene-ATP: further evidence for ATP and noradrenaline as cotransmitters.α,β-亚甲基三磷酸腺苷对豚鼠输精管兴奋性接头电位的抑制作用：三磷酸腺苷和去甲肾上腺素作为共同递质的进一步证据
Eur J Pharmacol. 1984 Apr 13;100(1):85-90. doi: 10.1016/0014-2999(84)90318-2.
3
Pharmacological evidence that adenosine triphosphate and noradrenaline are co-transmitters in the guinea-pig vas deferens.三磷酸腺苷和去甲肾上腺素作为豚鼠输精管中共同递质的药理学证据。
J Physiol. 1984 Feb;347:561-80. doi: 10.1113/jphysiol.1984.sp015083.
4
Noradrenaline receptors on the rat basilar artery.大鼠基底动脉上的去甲肾上腺素受体。
J Physiol. 1982 Jul;328:351-60. doi: 10.1113/jphysiol.1982.sp014268.
5
Electrophysiological analysis of the nature of adrenoceptors in the rat basilar artery during development.大鼠基底动脉发育过程中肾上腺素能受体性质的电生理分析
Br J Pharmacol. 1985 Sep;86(1):217-27. doi: 10.1111/j.1476-5381.1985.tb09452.x.
6
Actions of ATP and alpha, beta-methylene ATP on neuromuscular transmission and smooth muscle membrane of the rabbit and guinea-pig mesenteric arteries.ATP和α,β-亚甲基ATP对兔和豚鼠肠系膜动脉神经肌肉传递及平滑肌膜的作用
Br J Pharmacol. 1985 Dec;86(4):777-87. doi: 10.1111/j.1476-5381.1985.tb11099.x.