• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Do antimicrobial peptides and antimicrobial-peptide resistance play important roles during bacterial infection?抗菌肽及抗菌肽抗性在细菌感染过程中发挥重要作用吗？
Future Microbiol. 2018 Aug;13(10):1073-1075. doi: 10.2217/fmb-2018-0138. Epub 2018 Aug 16.
2
Surviving innate immunity.存活的固有免疫
Trends Microbiol. 2002 Aug;10(8):358-9. doi: 10.1016/s0966-842x(02)02406-x.
3
Bacterial resistance to antimicrobial peptides.细菌对抗菌肽的耐药性。
Biochim Biophys Acta. 2015 Nov;1848(11 Pt B):3019-20. doi: 10.1016/j.bbamem.2015.08.009. Epub 2015 Sep 3.
4
Understanding bacterial resistance to antimicrobial peptides: From the surface to deep inside.了解细菌对抗菌肽的耐药性：从表面到内部深处
Biochim Biophys Acta. 2015 Nov;1848(11 Pt B):3078-88. doi: 10.1016/j.bbamem.2015.02.017. Epub 2015 Feb 24.
5
Bacterial resistance to cationic antimicrobial peptides.细菌对阳离子抗菌肽的耐药性。
Crit Rev Microbiol. 2013 May;39(2):180-95. doi: 10.3109/1040841X.2012.699025. Epub 2012 Jul 16.
6
How do bacteria resist human antimicrobial peptides?细菌如何抵抗人类抗菌肽？
Trends Microbiol. 2002 Apr;10(4):179-86. doi: 10.1016/s0966-842x(02)02333-8.
7
Antimicrobial peptides: Opportunities and challenges in overcoming resistance.抗菌肽：克服耐药性的机遇与挑战。
Microbiol Res. 2024 Sep;286:127822. doi: 10.1016/j.micres.2024.127822. Epub 2024 Jun 26.
8
Antibacterial activity of the recombinant antimicrobial peptide Ib-AMP4 from Impatiens balsamina and its synergy with other antimicrobial agents against drug resistant bacteria.凤仙花重组抗菌肽Ib-AMP4的抗菌活性及其与其他抗菌剂对耐药菌的协同作用。
Pharmazie. 2013 Jul;68(7):628-30.
9
Staphylococcal resistance to antimicrobial peptides of mammalian and bacterial origin.葡萄球菌对哺乳动物和细菌来源抗菌肽的耐药性。
Peptides. 2001 Oct;22(10):1651-9. doi: 10.1016/s0196-9781(01)00500-9.
10
Bacteriophages, phage endolysins and antimicrobial peptides - the possibilities for their common use to combat infections and in the design of new drugs.噬菌体、噬菌体溶菌酶和抗菌肽——它们联合用于对抗感染及新药设计的可能性。
Ann Agric Environ Med. 2019 Jun 17;26(2):203-209. doi: 10.26444/aaem/105390. Epub 2019 Apr 11.

引用本文的文献

1
Identification and Characterization of a Novel Cathelicidin from with Antimicrobial and Anti-Inflammatory Activity.从 中鉴定和表征一种新型抗菌肽 cathelicidin，具有抗菌和抗炎活性。
Molecules. 2023 Feb 23;28(5):2082. doi: 10.3390/molecules28052082.
2
The Potential of Human Peptide LL-37 as an Antimicrobial and Anti-Biofilm Agent.人源肽LL-37作为抗菌和抗生物膜剂的潜力
Antibiotics (Basel). 2021 May 29;10(6):650. doi: 10.3390/antibiotics10060650.
3
Expression levels of pro-inflammatory interleukin-8 and certain antimicrobial peptides in concurrent with bacterial conjunctivitis.促炎白细胞介素-8和某些抗菌肽的表达水平与细菌性结膜炎并发。
Int J Ophthalmol. 2021 May 18;14(5):666-675. doi: 10.18240/ijo.2021.05.05. eCollection 2021.
4
LHH1, a novel antimicrobial peptide with anti-cancer cell activity identified from Lactobacillus casei HZ1.LHH1，一种从干酪乳杆菌HZ1中鉴定出的具有抗癌细胞活性的新型抗菌肽。
AMB Express. 2020 Nov 11;10(1):204. doi: 10.1186/s13568-020-01139-8.
5
Resistance Evolution Against Antimicrobial Peptides in Alters Pharmacodynamics Beyond the MIC.抗菌肽抗性进化改变了最低抑菌浓度（MIC）之外的药效学。
Front Microbiol. 2020 Feb 14;11:103. doi: 10.3389/fmicb.2020.00103. eCollection 2020.

本文引用的文献

1
Antimicrobial Peptide Resistance Mechanism Contributes to Staphylococcus aureus Infection.抗菌肽耐药机制导致金黄色葡萄球菌感染。
J Infect Dis. 2018 Mar 13;217(7):1153-1159. doi: 10.1093/infdis/jiy024.
2
Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance.抗药性时代的新型抗生素：针对有害细菌的抗毒力策略。
Nat Rev Drug Discov. 2017 Jul;16(7):457-471. doi: 10.1038/nrd.2017.23. Epub 2017 Mar 24.
3
Bacterial subversion of cAMP signalling inhibits cathelicidin expression, which is required for innate resistance to Mycobacterium tuberculosis.细菌对环磷酸腺苷（cAMP）信号传导的破坏会抑制杀菌肽的表达，而杀菌肽是对结核分枝杆菌天然抗性所必需的。
J Pathol. 2017 May;242(1):52-61. doi: 10.1002/path.4878. Epub 2017 Mar 15.
4
Bacterial strategies of resistance to antimicrobial peptides.细菌对抗菌肽的耐药策略。
Philos Trans R Soc Lond B Biol Sci. 2016 May 26;371(1695). doi: 10.1098/rstb.2015.0292.
5
Cathelicidin augments epithelial receptivity and pathogenesis in experimental Escherichia coli cystitis.在实验性大肠杆菌膀胱炎中，杀菌肽增强上皮细胞的易感性和发病机制。
J Infect Dis. 2015 Apr 1;211(7):1164-73. doi: 10.1093/infdis/jiu577. Epub 2014 Oct 21.
6
Crystal structure and functional mechanism of a human antimicrobial membrane channel.人抗菌膜通道的晶体结构和功能机制。
Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4586-91. doi: 10.1073/pnas.1214739110. Epub 2013 Feb 20.
7
Essential Staphylococcus aureus toxin export system.必需的金黄色葡萄球菌毒素外排系统。
Nat Med. 2013 Mar;19(3):364-7. doi: 10.1038/nm.3047. Epub 2013 Feb 10.
8
The antimicrobial peptide cathelicidin protects mice from Escherichia coli O157:H7-mediated disease.抗菌肽 cathelicidin 可保护小鼠免受大肠杆菌 O157:H7 引起的疾病。
PLoS One. 2012;7(10):e46476. doi: 10.1371/journal.pone.0046476. Epub 2012 Oct 15.
9
Human beta-defensin 3 inhibits cell wall biosynthesis in Staphylococci.人β-防御素 3 抑制葡萄球菌的细胞壁生物合成。
Infect Immun. 2010 Jun;78(6):2793-800. doi: 10.1128/IAI.00688-09. Epub 2010 Apr 12.
10
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.缺乏cathelicidin（Cnlp -/-）的小鼠对铜绿假单胞菌角膜炎的易感性增加。
Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4498-508. doi: 10.1167/iovs.07-0274.

Do antimicrobial peptides and antimicrobial-peptide resistance play important roles during bacterial infection?

作者信息

Cheung Gordon Yc, Otto Michael

机构信息

Pathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy & Infectious Diseases, US National Institutes of Health, 50 South Drive, Bethesda, MD 20814, USA.

出版信息

Future Microbiol. 2018 Aug;13(10):1073-1075. doi: 10.2217/fmb-2018-0138. Epub 2018 Aug 16.

DOI:10.2217/fmb-2018-0138
PMID:30113237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6190238/
Abstract
摘要