Ross Elyse, Barnett Rebecca, Tudhope Rebecca, Vasudev Kamini
Department of Psychiatry, Strathroy Middlesex General Hospital, Strathroy, ON, Canada.
J Clin Psychopharmacol. 2018 Oct;38(5):447-453. doi: 10.1097/JCP.0000000000000931.
Patients with severe mental illness are at risk of medical complications, including cardiovascular disease, metabolic syndrome, and diabetes. Given this vulnerability, combined with metabolic risks of antipsychotics, physical health monitoring is critical. Inpatient admission is an opportunity to screen for medical comorbidities. Our objective was to improve the rates of physical health monitoring on an inpatient psychiatry unit through implementation of an electronic standardized order set.
Using a clinical audit tool, we completed a baseline retrospective audit (96 eligible charts) of patients aged 18 to 100 years, discharged between January and March 2012, prescribed an antipsychotic for 3 or more days. We then developed and implemented a standard electronic admission order set and provided training to inpatient clinical staff. We completed a second chart audit of patients discharged between January and March 2016 (190 eligible charts) to measure improvement in physical health monitoring and intervention rates for abnormal results.
In the 2012 audit, thyroid-stimulating hormone (TSH), blood pressure, blood glucose, fasting lipids, electrocardiogram (ECG), and height/weight were measured in 71%, 92%, 31%, 36%, 51%, and 75% of patients, respectively. In the 2016 audit, TSH, blood pressure, blood glucose, fasting lipids, ECG, and height/weight were measured in 86%, 96%, 96%, 64%, 87%, and 71% of patients, respectively. There were statistically significant improvements (P < 0.05) in monitoring rates for blood glucose, lipids, ECG, and TSH. Intervention rates for abnormal blood glucose and/or lipids (feedback to family doctor and/or patient, consultation to hospitalist, endocrinology, and/or dietician) did not change between 2012 and 2016.
Electronic standardized order set can be used as a tool to improve screening for physical health comorbidity in patients with severe mental illness receiving antipsychotic medications.
患有严重精神疾病的患者有发生包括心血管疾病、代谢综合征和糖尿病在内的医学并发症的风险。鉴于这种易感性,再加上抗精神病药物的代谢风险,身体健康监测至关重要。住院是筛查合并症的一个机会。我们的目标是通过实施电子标准化医嘱集来提高住院精神科病房的身体健康监测率。
我们使用临床审计工具,对2012年1月至3月期间出院的18至100岁、服用抗精神病药物3天或更长时间的患者进行了基线回顾性审计(96份符合条件的病历)。然后,我们制定并实施了标准电子入院医嘱集,并为住院临床工作人员提供了培训。我们对2016年1月至3月期间出院的患者进行了第二次病历审计(190份符合条件的病历),以衡量身体健康监测和异常结果干预率的改善情况。
在2012年的审计中,分别对71%、92%、31%、36%、51%和75%的患者进行了促甲状腺激素(TSH)、血压、血糖、空腹血脂、心电图(ECG)以及身高/体重的测量。在2016年的审计中,分别对86%、96%、96%、64%、87%和71%的患者进行了TSH、血压、血糖、空腹血脂、ECG以及身高/体重的测量。血糖、血脂、ECG和TSH的监测率有统计学显著改善(P < 0.05)。2012年至2016年期间,异常血糖和/或血脂的干预率(反馈给家庭医生和/或患者、咨询住院医师、内分泌科医生和/或营养师)没有变化。
电子标准化医嘱集可作为一种工具,用于改善接受抗精神病药物治疗的严重精神疾病患者的身体健康合并症筛查。