使用自动在线固相萃取结合超高效液相色谱-串联质谱法测定人血浆中的阿哌沙班、达比加群、依度沙班和利伐沙班及其与凝血测定的比较。 - Suppr

Measurement of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma using automated online solid-phase extraction combined with ultra-performance liquid chromatography-tandem mass spectrometry and its comparison with coagulation assays.

作者信息

Kuhn Joachim, Gripp Tatjana, Flieder Tobias, Hammerschmidt Andreas, Hendig Doris, Faust Isabel, Knabbe Cornelius, Birschmann Ingvild

机构信息

Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center, Ruhr University Bochum, 32545 Bad Oeynhausen, Germany.

出版信息

Clin Chim Acta. 2018 Nov;486:347-356. doi: 10.1016/j.cca.2018.08.017. Epub 2018 Aug 13.

DOI:10.1016/j.cca.2018.08.017

PMID:30114406

Abstract

摘要

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Measurement of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma using automated online solid-phase extraction combined with ultra-performance liquid chromatography-tandem mass spectrometry and its comparison with coagulation assays.

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