Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3/311 Clinical Sciences Center, 600 Highland Avenue, Madison, WI 53792, USA.
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3/311 Clinical Sciences Center, 600 Highland Avenue, Madison, WI 53792, USA.
Gastroenterol Clin North Am. 2018 Sep;47(3):569-584. doi: 10.1016/j.gtc.2018.04.012. Epub 2018 Jul 7.
Although not traditionally used to assess hepatic fibrosis, computed tomography (CT) is fast, accessible, robust, and commonly used for abdominal indications. CT metrics are often easily retrospectively obtained without special equipment. Metrics such as liver segmental volume ratio, which quantifies regional hepatic volume changes; splenic volume; and liver surface nodularity scoring show diagnostic performance comparable to elastography techniques for detecting significant and advanced fibrosis. Other emerging CT tools, such as CT texture analysis and fractional extracellular volume, have also shown promise in identifying fibrosis and warrant further study.
虽然 CT 通常不用于评估肝纤维化，但它快速、易得、稳健，常用于腹部适应证。CT 指标通常可以轻松地从回顾性研究中获得，而无需特殊设备。肝段容积比等指标可以量化区域性肝体积变化；脾脏体积；以及肝表面结节评分显示出与弹性成像技术相当的诊断性能，可用于检测显著和晚期纤维化。其他新兴的 CT 工具，如 CT 纹理分析和细胞外容积分数，在识别纤维化方面也显示出了前景，值得进一步研究。
