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院外分娩:一项病例对照研究。

Out-of-hospital deliveries: A case-control study.

作者信息

Diana Lima, Glaucia Lima, Adriana Cersosimo, Israel Figueiredo

机构信息

Department of Materal and Child, Federal Fluminense University, Niterói, RJ, Brazil.

出版信息

Turk Pediatri Ars. 2018 Jun 1;53(2):87-95. doi: 10.5152/TurkPediatriArs.2018.6269. eCollection 2018 Jun.

Abstract

AIM

To identify the factors, risks, and mortality associated with unplanned out-of-hospital births.

MATERIAL AND METHODS

This observational, retrospective, case-control study was conducted between 2005 and 2013 through a review of medical records from the hospital network of a county of Brazil. Mother-child dyads were divided into in-hospital births and unplanned out-of-hospital births. For hypothesis testing involving quantitative variables, parametric and nonparametric methods (t-test or Mann-Whitney test, respectively) were used as appropriate after ascertaining normality of distribution via the Kolmogorov-Smirnov or Shapiro-Wilk tests. The chi-square test, Fisher's exact test, odds ratios, and 95% confidence intervals were used to assess the relationship between categorical variables. A binary logistic regression was applied for pooled analysis of those variables that, when analyzed in isolation, had significant p-values on hypothesis testing. In all tests, p-values <0.05 were considered statistically significant.

RESULTS

Of the 420 records, 117 corresponded to out-of-hospital births dyads. Mothers were predominantly nonwhite (p<0.001), with a history of inadequate antenatal care (p<0.001), multiparous (p<0.001), aged >25 years (p=0.031), and had more puerperal complications (p<0.001). Their newborns had low birth weight (Odds Ratios: 2.22; 95% CI: [1.4-3.4]; p<0.001), higher morbidity (p=0.009), a higher rate of admission to neonatal intensive care and stepdown units (p=0.030), and prolonged length of stay (p<0.001).

CONCLUSION

The risk of maternal and neonatal complications, as well as the neonatal mortality rate, were higher for unplanned out-of-hospital deliveries. It occurred predominantly in nonwhite, older, multiparous women who had received incomplete antenatal care and who lived far from perinatal care centers.

摘要

目的

确定与非计划院外分娩相关的因素、风险及死亡率。

材料与方法

本观察性、回顾性病例对照研究于2005年至2013年期间开展,通过查阅巴西某县医院网络的医疗记录进行。母婴二元组分为院内分娩和非计划院外分娩。对于涉及定量变量的假设检验,在通过柯尔莫哥洛夫-斯米尔诺夫检验或夏皮罗-威尔克检验确定分布正态性后,酌情使用参数和非参数方法(分别为t检验或曼-惠特尼检验)。卡方检验、费舍尔精确检验、比值比和95%置信区间用于评估分类变量之间的关系。对那些单独分析时在假设检验中具有显著p值的变量进行二元逻辑回归汇总分析。在所有检验中,p值<0.05被认为具有统计学意义。

结果

在420份记录中,117份对应院外分娩二元组。母亲主要为非白人(p<0.001),有产前护理不足史(p<0.001),经产妇(p<0.001),年龄>25岁(p=0.031),且产褥期并发症更多(p<0.001)。她们的新生儿出生体重低(比值比:2.22;95%置信区间:[1.4 - 3.4];p<0.001),发病率更高(p=0.009),入住新生儿重症监护病房和降级病房的比例更高(p=0.030),住院时间延长(p<0.001)。

结论

非计划院外分娩的孕产妇和新生儿并发症风险以及新生儿死亡率更高。这种情况主要发生在非白人、年龄较大、经产妇且产前护理不完整且居住在远离围产期护理中心的妇女中。

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