Turk J Med Sci. 2018 Aug 16;48(4):768-776. doi: 10.3906/sag-1712-12.
BACKGROUND/AIM: We compared the effects of volume-controlled equal ratio ventilation (VC-ERV) and volume-controlled conventional ratio ventilation (VC-CRV) on oxygenation, ventilation, respiratory mechanics, and hemodynamic status during mechanical ventilation with recruitment maneuver (RM) and positive end-expiratory pressure (PEEP) in patients undergoing laparoscopic sleeve gastrectomy.
A total of 111 patients scheduled for laparoscopic sleeve gastrectomy were randomized to ventilation with inspiratory to expiratory ratio of 1:1 (Group VC-ERV) or 1:2 (Group VC-CRV) following tracheal intubation. RM (40 cmH2O, 15 s) and PEEP (10 cmH2O) were administered to all patients. Arterial blood gas samples were taken and peak airway pressure (Ppeak), mean airway pressure (Pmean), dynamic compliance (Cdyn), mean arterial pressure, heart rate, SpO2, and EtCO2 were recorded at 4 time points. Postoperative respiratory complications were recorded.
Oxygenation, ventilation, Pmean levels, and hemodynamic variables were similar in both groups. VC-ERV significantly decreased Ppeak and increased Cdyn compared to VC-CRV at all time points of the operation (P < 0.05). No pulmonary complication was observed in any patients.
VC-ERV provides significantly lower Ppeak and higher Cdyn with similar oxygenation, ventilation, hemodynamic parameters, and Pmean levels when compared to VC-CRV during mechanical ventilation with RM and PEEP in laparoscopic sleeve gastrectomy.
背景/目的:我们比较了容量控制型等容通气(VC-ERV)和容量控制型传统比例通气(VC-CRV)在机械通气联合肺复张(RM)和呼气末正压(PEEP)时对行腹腔镜袖状胃切除术患者氧合、通气、呼吸力学和血流动力学的影响。
共 111 例行腹腔镜袖状胃切除术的患者在气管插管后随机分为吸气与呼气比例为 1:1(VC-ERV 组)或 1:2(VC-CRV 组)的通气组。所有患者均给予 RM(40cmH2O,15s)和 PEEP(10cmH2O)。在 4 个时间点采集动脉血气样本,并记录气道峰压(Ppeak)、平均气道压(Pmean)、动态顺应性(Cdyn)、平均动脉压、心率、SpO2和 EtCO2。记录术后呼吸并发症。
两组患者的氧合、通气、Pmean 水平和血流动力学变量相似。与 VC-CRV 相比,VC-ERV 在手术的所有时间点均显著降低 Ppeak 并增加 Cdyn(P<0.05)。所有患者均未发生肺部并发症。
与 VC-CRV 相比,在 RM 和 PEEP 联合机械通气治疗腹腔镜袖状胃切除术中,VC-ERV 可显著降低 Ppeak 并增加 Cdyn,而氧合、通气、血流动力学参数和 Pmean 水平相似。