Suppr超能文献

容量控制型等容通气联合肺复张及呼气末正压通气在腹腔镜袖状胃切除术中的应用:一项前瞻性、随机、对照试验。

Effects of volume-controlled equal ratio ventilation with recruitment maneuver and positive end-expiratory pressure in laparoscopic sleeve gastrectomy: a prospective, randomized, controlled trial.

出版信息

Turk J Med Sci. 2018 Aug 16;48(4):768-776. doi: 10.3906/sag-1712-12.

Abstract

BACKGROUND/AIM: We compared the effects of volume-controlled equal ratio ventilation (VC-ERV) and volume-controlled conventional ratio ventilation (VC-CRV) on oxygenation, ventilation, respiratory mechanics, and hemodynamic status during mechanical ventilation with recruitment maneuver (RM) and positive end-expiratory pressure (PEEP) in patients undergoing laparoscopic sleeve gastrectomy.

MATERIALS AND METHODS

A total of 111 patients scheduled for laparoscopic sleeve gastrectomy were randomized to ventilation with inspiratory to expiratory ratio of 1:1 (Group VC-ERV) or 1:2 (Group VC-CRV) following tracheal intubation. RM (40 cmH2O, 15 s) and PEEP (10 cmH2O) were administered to all patients. Arterial blood gas samples were taken and peak airway pressure (Ppeak), mean airway pressure (Pmean), dynamic compliance (Cdyn), mean arterial pressure, heart rate, SpO2, and EtCO2 were recorded at 4 time points. Postoperative respiratory complications were recorded.

RESULTS

Oxygenation, ventilation, Pmean levels, and hemodynamic variables were similar in both groups. VC-ERV significantly decreased Ppeak and increased Cdyn compared to VC-CRV at all time points of the operation (P < 0.05). No pulmonary complication was observed in any patients.

CONCLUSION

VC-ERV provides significantly lower Ppeak and higher Cdyn with similar oxygenation, ventilation, hemodynamic parameters, and Pmean levels when compared to VC-CRV during mechanical ventilation with RM and PEEP in laparoscopic sleeve gastrectomy.

摘要

背景/目的:我们比较了容量控制型等容通气(VC-ERV)和容量控制型传统比例通气(VC-CRV)在机械通气联合肺复张(RM)和呼气末正压(PEEP)时对行腹腔镜袖状胃切除术患者氧合、通气、呼吸力学和血流动力学的影响。

材料和方法

共 111 例行腹腔镜袖状胃切除术的患者在气管插管后随机分为吸气与呼气比例为 1:1(VC-ERV 组)或 1:2(VC-CRV 组)的通气组。所有患者均给予 RM(40cmH2O,15s)和 PEEP(10cmH2O)。在 4 个时间点采集动脉血气样本,并记录气道峰压(Ppeak)、平均气道压(Pmean)、动态顺应性(Cdyn)、平均动脉压、心率、SpO2和 EtCO2。记录术后呼吸并发症。

结果

两组患者的氧合、通气、Pmean 水平和血流动力学变量相似。与 VC-CRV 相比,VC-ERV 在手术的所有时间点均显著降低 Ppeak 并增加 Cdyn(P<0.05)。所有患者均未发生肺部并发症。

结论

与 VC-CRV 相比,在 RM 和 PEEP 联合机械通气治疗腹腔镜袖状胃切除术中,VC-ERV 可显著降低 Ppeak 并增加 Cdyn,而氧合、通气、血流动力学参数和 Pmean 水平相似。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验