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钝性胸部损伤患者的长期预后和健康相关生活质量:叙事文献综述。

The long-term outcomes and health-related quality of life of patients following blunt thoracic injury: a narrative literature review.

机构信息

Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, James Clerk Maxwell Building, 57 Waterloo Road, London, SE1 8WA, UK.

Emergency Department, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK.

出版信息

Scand J Trauma Resusc Emerg Med. 2018 Aug 17;26(1):67. doi: 10.1186/s13049-018-0535-9.

Abstract

BACKGROUND

Major Trauma remains a leading cause of mortality and morbidity worldwide. Blunt Thoracic Injury (BTI) accounts for > 15% of United Kingdom (UK) trauma admissions and is consistently associated with respiratory related complications that include pneumonia and respiratory failure. Despite this, it is unclear in current clinical practice how BTI impacts on the recovering trauma patients after discharge from hospital. This study aimed to investigate the state of knowledge on the impact of BTI on the long-term outcomes and health-related quality of life (HRQoL).

METHODS

Data were sourced from Ovid MEDLINE, Ovid EMBASE, CINAHL and Science Direct using a pre-defined systematic search strategy. A subsequent hand search of key references was used to identify potentially missed studies. Abstracts were screened for eligibility and inclusion. Fifteen studies met the eligibility criteria and were critically appraised. Data were extracted, analysed and synthesised in categories and sub-categories following a narrative approach.

RESULTS

Three major themes were identified from the 15 studies included in this review: (i) physical impact of BTI, (ii) psychological impact of BTI and (iii) socio-economic impact of BTI. The bulk of the available data focused on the physical impact where further sub-themes included: (i) physical functioning, (ii) ongoing unresolved pain, (iii) reduced respiratory function, (iv) thoracic structural integrity. Although there was a substantial difference in the length and method of follow up, there remains a general trend towards physical symptoms improving over time, particularly over the first six months after injury. Despite this, where sequelae continued at six months it remained likely that these would also be present at two years after injury.

CONCLUSION

The literature review demonstrated that BTI is associated with substantial sequelae that impacts on all aspects of daily functioning. Despite this there remains a paucity of data relating to long term outcomes in the BTI population, especially relating to psychological and socio-economic impact. There is also little consensus on the measures, tools and time-frames used to measure outcomes and HRQoL in this population. The full impact of BTI on this population needs further exploration.

摘要

背景

严重创伤仍然是全球范围内导致死亡和发病的主要原因。钝性胸部损伤(BTI)占英国(UK)创伤入院人数的>15%,并且始终与包括肺炎和呼吸衰竭在内的呼吸相关并发症相关。尽管如此,目前在临床实践中尚不清楚 BTI 对出院后创伤患者的恢复有何影响。本研究旨在调查 BTI 对长期结果和健康相关生活质量(HRQoL)的影响的知识状态。

方法

使用预先确定的系统搜索策略,从 Ovid MEDLINE、Ovid EMBASE、CINAHL 和 Science Direct 中获取数据。随后,对手头的关键参考文献进行了搜索,以确定可能遗漏的研究。筛选摘要以确定是否符合入选标准。符合入选标准的 15 项研究进行了批判性评估。按照叙述性方法,将数据分类和分项提取、分析和综合。

结果

从纳入本综述的 15 项研究中确定了三个主要主题:(i)BTI 的身体影响,(ii)BTI 的心理影响和(iii)BTI 的社会经济影响。大部分现有数据集中在身体影响上,进一步的子主题包括:(i)身体功能,(ii)持续未解决的疼痛,(iii)呼吸功能降低,(iv)胸壁结构完整性。尽管随访的时间和方法存在很大差异,但仍有一个普遍的趋势,即身体症状随时间改善,尤其是在受伤后的前六个月。尽管如此,如果六个月后仍有后遗症,那么在受伤后两年也很可能会出现后遗症。

结论

文献综述表明,BTI 与严重的后遗症有关,这些后遗症会影响日常功能的各个方面。尽管如此,关于 BTI 人群的长期结果的数据仍然很少,尤其是关于心理和社会经济影响的数据。在这个人群中,用于测量结果和 HRQoL 的措施、工具和时间框架也没有达成共识。BTI 对这一人群的全面影响需要进一步探索。

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