Tauziède-Espariat Arnault, Raffoul Johnny, Sun Shan Rong, Lassabe Catherine, Monnin Christine
Service de pathologie, centre hospitalier Montbéliard, 12, rue Docteur Flamand, 25200 Montbéliard, France.
Service de pathologie, centre hospitalier Montbéliard, 12, rue Docteur Flamand, 25200 Montbéliard, France.
Ann Pathol. 2018 Dec;38(6):386-390. doi: 10.1016/j.annpat.2018.06.002. Epub 2018 Aug 16.
We report the case of a Caucasian 73-year-old woman, without medical history, who is operated of two lesions of the forehead and the scalp measuring 0.4 and 1cm. There is no adenopathy. Histopathological examination revealed a diffuse vascular proliferation of the dermis and the hypodermis composed of small vessels bordered of plump "epthelioid" endothelial cells. There is no mitotic figure. The stroma is slightly fibrous accompanied by a polymorphic inflammatory infiltrate rich in lymphocytes, sometimes arranged in lymphoid follicles, plasma cells and eosinophils. The proposed diagnosis is angiolymphoid hyperplasia with eosinophilia. This is a rare vascular tumor, benign according with the OMS classification and preferentially observed in the skin. We report a cutaneous case, clinical and histopathological data of the reported cases and present the main differential diagnoses.
我们报告了一例73岁的白种女性病例，该患者无病史，因额头和头皮上分别有大小为0.4厘米和1厘米的两处病变而接受手术治疗。未发现淋巴结肿大。组织病理学检查显示真皮和皮下组织有弥漫性血管增生，由小血管组成，血管边界为丰满的“上皮样”内皮细胞。未见有丝分裂象。间质轻度纤维化，伴有多形性炎症浸润，富含淋巴细胞，有时排列成淋巴滤泡、浆细胞和嗜酸性粒细胞。拟诊断为嗜酸性粒细胞增多性血管淋巴样增生。这是一种罕见的血管肿瘤，根据世界卫生组织（WHO）分类为良性，多见于皮肤。我们报告了该皮肤病例、已报道病例的临床和组织病理学数据，并介绍了主要的鉴别诊断。
