TREM 样转录本 1：在人类和小鼠中比 P 选择素更敏感的血小板活化标志物。
TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice.
机构信息
Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
出版信息
Blood Adv. 2018 Aug 28;2(16):2072-2078. doi: 10.1182/bloodadvances.2018017756.
Abstract
Platelet activation in vitro results in a more rapid and greater upregulation of TLT-1 surface expression compared with P-selectin. TLT-1 is more rapidly translocated to the surface of activated platelets than P-selectin during thrombus formation in vivo.
摘要
与 P-选择素相比，体外血小板激活导致 TLT-1 表面表达的更快和更大上调。在体内血栓形成过程中，TLT-1 比 P-选择素更快地转位到活化血小板的表面。
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