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接受体外膜肺氧合治疗的急性呼吸窘迫综合征患者的院际转运

Interhospital transport of ARDS patients on extracorporeal membrane oxygenation.

作者信息

Heuer Jan Florian, Mirschel Moritz, Bleckmann Annalen, Quintel Michael, Moerer Onnen

机构信息

Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Management, Augusta-Kliniken Bochum-Mitte, Bochum, Germany.

Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Management, University Medical Center Göttingen, Göttingen, Germany.

出版信息

J Artif Organs. 2019 Mar;22(1):53-60. doi: 10.1007/s10047-018-1065-y. Epub 2018 Aug 18.

Abstract

Veno-venous extracorporeal membrane oxygenation (ECMO) can be a lifesaving therapy for patients with severe acute respiratory distress syndrome (ARDS). ECMO is a technically complex and challenging procedure and should therefore only be performed in specialized centers. Transporting ARDS patients to ECMO centers for treatment can be dangerous because of the risk of hypoxemia during transport. This raises the question if ECMO should not be already initiated in the transferring hospital before transport. Over a 5-year period, we studied ARDS patients who had been transported to our department by our mobile ECMO team for further treatment after ECMO had already been initiated at the referring hospital. Data for analysis were obtained from our patient data management system (PDMS), the referral documents, and from the referring hospitals. Seventy-five patients meeting the selection criteria were studied. All had been successfully cannulated in the transferring hospitals. They were transported to our ECMO center by helicopter (n = 34) or mobile intensive care units (n = 41). No patient died during transport. Forty four of the patients were transported at night. Twenty-six patients (35%) died in our intensive care unit due to a therapy refractory course, comorbidities or limitation of therapy. Patients on ECMO therapy can be safely transferred to a specialist center. Setting up ECMO in an unfamiliar location and the subsequent patient transport can be very challenging and should only be performed by a highly trained, experienced team.

摘要

静脉-静脉体外膜肺氧合(ECMO)对于严重急性呼吸窘迫综合征(ARDS)患者可能是一种挽救生命的治疗方法。ECMO是一项技术复杂且具有挑战性的操作,因此应仅在专业中心进行。由于转运过程中存在低氧血症风险,将ARDS患者转运至ECMO中心进行治疗可能很危险。这就引发了一个问题,即在转运前是否不应在转诊医院就启动ECMO。在5年的时间里,我们研究了由我们的移动ECMO团队转运至我科的ARDS患者,这些患者在转诊医院已启动ECMO后前来接受进一步治疗。分析数据来自我们的患者数据管理系统(PDMS)、转诊文件以及转诊医院。对75名符合选择标准的患者进行了研究。所有患者均在转诊医院成功插管。他们通过直升机(n = 34)或移动重症监护单元(n = 41)被转运至我们的ECMO中心。转运过程中无患者死亡。44名患者在夜间被转运。26名患者(35%)在我们的重症监护病房因治疗难治性病程、合并症或治疗受限而死亡。接受ECMO治疗的患者可以安全地转运至专科中心。在不熟悉的地点建立ECMO并随后转运患者可能极具挑战性,且应由训练有素、经验丰富的团队进行。

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