Chandawale Shirish S, Karia Kunjal Mukesh, Agrawal Neekita S, Patil Amardeep A, Shetty Abhinav B, Kaur Manpreet
Department of Pathology, Dr. D. Y. Patil Medical College, Pune, Maharashtra, India.
Int J Appl Basic Med Res. 2018 Jul-Sep;8(3):193-195. doi: 10.4103/ijabmr.IJABMR_119_17.
Uterine lipoleiomyoma and pure lipoma are uncommon and extremely rare benign lipomatous tumors. Reported incidence is 0.03%-0.25%. Pure cervical lipoma is exceptionally rare. These tumors commonly arise in postmenopausal women. Ultrasonography and computed tomography finding may be nonspecific. Although magnetic resonance imaging can be useful in identifying the fatty nature of the lesion preoperatively, most of the cases postoperatively on histopathological examination. Although various theories of histogenesis of these tumors have been proposed, histogenesis remains to be enigma. These lesions may have coexistent malignancy in uterus, ovaries, and fallopian tubes or may have other metabolic disorders and abnormal estrogen status. Immunohistochemical studies have played an integral role in understanding its complex histogenesis. We did not find any case study in medical literature in which uterine lipoleiomyoma and cervical lipoma have been described in hysterectomy specimen. We report a unique case of a 43-year-old premenopausal woman with complaints of irregular vaginal bleeding and lower abdomen pain. Lipoleiomyoma in uterus corpus and cervical lipoma were diagnosed in hysterectomy specimen.
子宫脂肪平滑肌瘤和纯脂肪瘤是罕见的良性脂肪瘤性肿瘤。报告的发病率为0.03%-0.25%。纯宫颈脂肪瘤极为罕见。这些肿瘤常见于绝经后女性。超声检查和计算机断层扫描结果可能不具有特异性。虽然磁共振成像有助于术前识别病变的脂肪性质,但大多数病例需术后进行组织病理学检查。尽管已提出了这些肿瘤的各种组织发生学理论,但组织发生学仍是个谜。这些病变可能与子宫、卵巢和输卵管的恶性肿瘤并存,或可能有其他代谢紊乱和异常雌激素状态。免疫组织化学研究在理解其复杂的组织发生学中发挥了不可或缺的作用。我们在医学文献中未发现任何关于子宫脂肪平滑肌瘤和宫颈脂肪瘤在子宫切除标本中描述的病例研究。我们报告了一例独特的病例,一名43岁的绝经前女性,主诉不规则阴道出血和下腹部疼痛。子宫切除标本中诊断出子宫体部脂肪平滑肌瘤和宫颈脂肪瘤。