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[Gamma-aminobutyric acid receptors in the central nervous system of mammals].

作者信息

Valeev A E

出版信息

Neirofiziologiia. 1986;18(2):273-82.

PMID:3012383
Abstract

The review describes properties of gamma-aminobutyric acid (GABA) receptors in the central nervous system of mammalians. Two pharmacologically different receptors--GABAA and GABAB--are involved into GABA-ergic inhibition. GABA receptors (bicuculline-sensitive) regulate chloride permeability of membranes and can be functionally enhanced by benzodiazepine and barbiturate. GABA receptors (bicuculline-insensitive) are suggested to regulate calcium permeability.

摘要

相似文献

1
[Gamma-aminobutyric acid receptors in the central nervous system of mammals].
Neirofiziologiia. 1986;18(2):273-82.
2
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Chloride homeostasis differentially affects GABA(A) receptor- and glycine receptor-mediated effects on spontaneous circuit activity in hippocampal cell culture.氯离子稳态对海马细胞培养中γ-氨基丁酸A(GABA(A))受体和甘氨酸受体介导的自发回路活动的影响存在差异。
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[Benzodiazepine receptors in the central nervous system of mammals].[哺乳动物中枢神经系统中的苯二氮䓬受体]
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Characterization of bicuculline/baclofen-insensitive (rho-like) gamma-aminobutyric acid receptors expressed in Xenopus oocytes. II. Pharmacology of gamma-aminobutyric acidA and gamma-aminobutyric acidB receptor agonists and antagonists.非洲爪蟾卵母细胞中表达的荷包牡丹碱/巴氯芬不敏感(rho样)γ-氨基丁酸受体的特性。II. γ-氨基丁酸A和γ-氨基丁酸B受体激动剂及拮抗剂的药理学
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Pharmacology of GABA receptor Cl- channels in rat retinal bipolar cells.大鼠视网膜双极细胞中γ-氨基丁酸(GABA)受体氯离子通道的药理学
Nature. 1993 Jan 14;361(6408):159-62. doi: 10.1038/361159a0.
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Barbiturate and benzodiazepine modulation of GABA receptor binding and function.巴比妥类和苯二氮䓬类对GABA受体结合及功能的调节作用。
Life Sci. 1986 Nov 24;39(21):1969-76. doi: 10.1016/0024-3205(86)90320-6.
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Nitric oxide mediates interactions between GABAA receptors and adenosine A1 receptors in the rat hippocampus.一氧化氮介导大鼠海马体中γ-氨基丁酸A型受体(GABAA受体)与腺苷A1受体之间的相互作用。
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Divergent alterations in gamma-aminobutyric acid responses of male and ovariectomized rats after chronic benzodiazepine agonist exposure: analysis of gamma-aminobutyric acid-activated chloride influx.慢性苯二氮䓬激动剂暴露后雄性大鼠和去卵巢大鼠γ-氨基丁酸反应的不同改变:γ-氨基丁酸激活的氯离子内流分析
J Pharmacol Exp Ther. 1993 Aug;266(2):768-73.

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