新生儿先天性感染诊断实用指南。

A practical guide to the diagnosis of congenital infections in the newborn infant.

作者信息

Alpert G, Plotkin S A

出版信息

Pediatr Clin North Am. 1986 Jun;33(3):465-79. doi: 10.1016/s0031-3955(16)36037-0.

Abstract

Every attempt should be made to identify an etiologic agent in infants with suspected congenital infection. Some of the infections are treatable, such as herpes simplex, syphilis, and toxoplasmosis. For other infectious agents (i.e., CMV and rubella), close follow-up will enable early detection of hearing impairment and permit early educational intervention. In addition, appropriate isolation measures will reduce the risk of nosocomial infections due to herpes simplex, rubella, hepatitis B, and CMV. Rational use of the available diagnostic tools will enable detection of most symptomatic congenitally infected neonates at a reasonable cost.

摘要

对于疑似先天性感染的婴儿，应尽一切努力确定病原体。有些感染是可治疗的，如单纯疱疹、梅毒和弓形虫病。对于其他感染因子（即巨细胞病毒和风疹），密切随访将有助于早期发现听力障碍并允许早期进行教育干预。此外，适当的隔离措施将降低因单纯疱疹、风疹、乙型肝炎和巨细胞病毒导致医院感染的风险。合理使用现有的诊断工具将能够以合理的成本检测出大多数有症状的先天性感染新生儿。