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Pharmacokinetics and metabolism of delta 1-tetrahydrocannabinol and other cannabinoids with emphasis on man.

作者信息

Agurell S, Halldin M, Lindgren J E, Ohlsson A, Widman M, Gillespie H, Hollister L

出版信息

Pharmacol Rev. 1986 Mar;38(1):21-43.

PMID:3012605
Abstract
摘要

相似文献

1
Pharmacokinetics and metabolism of delta 1-tetrahydrocannabinol and other cannabinoids with emphasis on man.
Pharmacol Rev. 1986 Mar;38(1):21-43.
2
Plasma cannabinoids measured by radioimmunoassay in rabbits after intravenous injection of tetrahydrocannibinol, 11-hydroxy-tetrahydrocannabinol, cannabinol and cannabidiol.
Res Commun Chem Pathol Pharmacol. 1975 Jun;11(2):339-42.
3
Comparative pharmacology of Delta9-tetrahydrocannabinol and its metabolite, 11-OH-Delta9-tetrahydrocannabinol.Δ9-四氢大麻酚及其代谢物11-羟基-Δ9-四氢大麻酚的比较药理学
J Clin Invest. 1973 Oct;52(10):2411-7. doi: 10.1172/JCI107431.
4
Metabolism and disposition of delta-9-tetrahydrocannabinol in man.人体内 Δ⁹-四氢大麻酚的代谢与处置
Pharmacol Rev. 1971 Dec;23(4):371-80.
5
Biological disposition of tetrahydrocannabinols.
Pharmacol Rev. 1971 Dec;23(4):273-8.
6
Human effects.对人类的影响。
NIDA Res Monogr. 1977 Jul(14):128-78.
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The constituents of cannabis and the disposition and metabolism of cannabinoids.
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Chemistry of marihuana.大麻的化学性质。
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Effects of delta 9-tetrahydrocannabinol and cannabidiol on sodium-dependent high affinity choline uptake in the rat hippocampus.δ9-四氢大麻酚和大麻二酚对大鼠海马体中钠依赖性高亲和力胆碱摄取的影响。
J Pharmacol Exp Ther. 1980 May;213(2):216-21.
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Metabolic disposition of delta 8-tetrahydrocannabinol and its active metabolites, 11-hydroxy-delta 8-tetrahydrocannabinol and 11-oxo-delta 8-tetrahydrocannabinol, in mice.δ8-四氢大麻酚及其活性代谢物11-羟基-δ8-四氢大麻酚和11-氧代-δ8-四氢大麻酚在小鼠体内的代谢情况。
Drug Metab Dispos. 1981 May-Jun;9(3):261-4.

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CYP2C9、CYP3A 和 CYP2C19 将 Δ9-四氢大麻酚代谢为多种代谢物，但代谢受人体肝脂肪酸结合蛋白（FABP1）的影响。
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