Department of Surgery, Division of GI/Minimally Invasive Surgery, Loyola University Medical Center, Stritch School of Medicine, Maywood, IL, USA.
Department of Surgery, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Songkhla, Thailand.
Obes Surg. 2019 Jan;29(1):54-60. doi: 10.1007/s11695-018-3444-0.
A preoperative very low-calorie diet (VLCD) is a common method to reduce weight before bariatric surgery. However, patient compliance and acceptability are not always known. The aim of this study is to evaluate the effectiveness, compliance, and acceptability of our regimen in a metropolitan academic quaternary care center.
Patients with a BMI < 50 kg/m and a BMI ≥ 50 kg/m were instructed to be on a liquid VLCD for 1 week and 2 weeks, respectively. The primary outcome was the amount of weight loss. Secondary outcomes were patient compliance and acceptability of either regimen using a questionnaire for hunger, satisfaction, desire, and deviation for solids.
The study included 128 patients. Ninety-four patients were in the BMI < 50 kg/m group, and 34 patients were in the BMI ≥ 50 kg/m group. The BMI ≥ 50 kg/m group had a greater percentage of total weight loss (mean ± SD) than that of the BMI < 50 kg/m group without statistical differences (4.4 ± 1.3% vs. 3.8 ± 1.6%, p = 0.072). There were no statistical differences between the groups in terms of hunger, satisfaction with a liquid diet, or satisfaction of eating over drinking. However, hunger sensation (median [IQR]) tended to be higher in the BMI < 50 kg/m group than that in the BMI ≥ 50 kg/m group (2 [2] vs. 2 [2, 3]; p = 0.06). There was no statistical difference in the percentage of patient compliance between the groups (75.5% [n = 71] vs. 61.8% [n = 21], p = 0.18).
Preoperative liquid VLCD provided a modest amount of weight loss and showed a high rate of patient compliance and acceptability.
术前极低热量饮食（VLCD）是减肥手术前常用的方法。然而，患者的依从性和可接受性并不总是为人所知。本研究旨在评估我们在都市学术四级保健中心的方案的有效性、依从性和可接受性。
BMI<50kg/m2和 BMI≥50kg/m2的患者分别接受为期 1 周和 2 周的液体 VLCD。主要结局是体重减轻量。次要结局是使用饥饿、满意度、渴望和固体偏差问卷评估两种方案的患者依从性和可接受性。
该研究共纳入 128 例患者。94 例患者 BMI<50kg/m2，34 例患者 BMI≥50kg/m2。BMI≥50kg/m2组的总体重减轻百分比（均值±标准差）大于 BMI<50kg/m2组，但无统计学差异（4.4±1.3%比 3.8±1.6%，p=0.072）。两组在饥饿感、对液体饮食的满意度或饮食满意度方面无统计学差异。然而，BMI<50kg/m2组的饥饿感（中位数[IQR]）高于 BMI≥50kg/m2组（2[2]比 2[2,3]；p=0.06）。两组患者的依从率无统计学差异（75.5%[n=71]比 61.8%[n=21]，p=0.18）。
术前液体 VLCD 可减轻适度体重，且患者的依从性和可接受性较高。
